RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) as new tools for cancer therapy: first steps from bench to bedside
Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …
been considered as 'junk'for a long time, non-coding RNAs are now well established as …
A comprehensive review of cancer MicroRNA therapeutic delivery strategies
A Forterre, H Komuro, S Aminova, M Harada - Cancers, 2020 - mdpi.com
In the field of molecular oncology, microRNAs (miRNAs) and their role in regulating
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
physiological processes and cancer pathogenesis have been a revolutionary discovery over …
Rational design of nanocarriers for intracellular protein delivery
Protein/antibody therapeutics have exhibited the advantages of high specificity and activity
even at an extremely low concentration compared to small molecule drugs. However, they …
even at an extremely low concentration compared to small molecule drugs. However, they …
Regulatory mechanisms of epigenetic miRNA relationships in human cancer and potential as therapeutic targets
Simple Summary By the virtue of targeting multiple genes, a microRNA (miRNA) can infer
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
variable consequences on tumorigenesis by appearing as both a tumour suppressor and …
COVID-19: fighting the invisible enemy with microRNAs
N Chauhan, M Jaggi, SC Chauhan… - Expert review of anti …, 2021 - Taylor & Francis
ABSTRACT Introduction The novel coronavirus (CoV) disease 2019 (COVID-19) is a viral
infection that causes severe acute respiratory syndrome (SARS). It is believed that early …
infection that causes severe acute respiratory syndrome (SARS). It is believed that early …
Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases
Background Researchers now have a new avenue to investigate when it comes to miRNA-
based therapeutics. miRNAs have the potential to be valuable biomarkers for disease …
based therapeutics. miRNAs have the potential to be valuable biomarkers for disease …
Nanosystems as vehicles for the delivery of antimicrobial peptides (AMPs)
Á Martin-Serrano, R Gómez, P Ortega, FJ de la Mata - Pharmaceutics, 2019 - mdpi.com
Recently, antimicrobial peptides (AMPs), also called host defence peptides (HDPs), are
attracting great interest, as they are a highly viable alternative in the search of new …
attracting great interest, as they are a highly viable alternative in the search of new …
MiRNA-SARS-CoV-2 dialogue and prospective anti-COVID-19 therapies
COVID-19 is a highly transmissible disease caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), affects 226 countries and continents, and has resulted in> 6.2 …
coronavirus-2 (SARS-CoV-2), affects 226 countries and continents, and has resulted in> 6.2 …
Recent advances in nanotechnology approaches for non-viral gene therapy
Gene therapy has shown great potential in the treatment of many diseases by
downregulating the expression of certain genes. The development of gene vectors as a …
downregulating the expression of certain genes. The development of gene vectors as a …