Cancer chemoresistance and its mechanisms: Associated molecular factors and its regulatory role

S Kannampuzha, AV Gopalakrishnan - Medical Oncology, 2023 - Springer
Cancer therapy has advanced from tradition chemotherapy methods to targeted therapy,
novel drug delivery mechanisms, combination therapies etc. Although several novel …

The emerging role of noncoding RNAs in colorectal cancer chemoresistance

L Wei, X Wang, L Lv, Y Zheng, N Zhang, M Yang - Cellular oncology, 2019 - Springer
Background Colorectal cancer (CRC) is the third most prevalent cancer in the world and one
of the most lethal human malignancies. Chemotherapy with 5-fluorouracil, platinum …

Exosomal long non-coding RNAs in lung diseases

C Poulet, MS Njock, C Moermans, E Louis… - International journal of …, 2020 - mdpi.com
Within the non-coding genome landscape, long non-coding RNAs (lncRNAs) and their
secretion within exosomes are a window that could further explain the regulation, the …

[HTML][HTML] TGFβ1 promotes gemcitabine resistance through regulating the LncRNA-LET/NF90/miR-145 signaling axis in bladder cancer

J Zhuang, L Shen, L Yang, X Huang, Q Lu, Y Cui… - Theranostics, 2017 - ncbi.nlm.nih.gov
High tumor recurrence is frequently observed in patients with urinary bladder cancers
(UBCs), with the need for biomarkers of prognosis and drug response. Chemoresistance …

Application of long noncoding RNAs in osteosarcoma: biomarkers and therapeutic targets

Z Li, P Dou, T Liu, S He - Cellular Physiology and Biochemistry, 2017 - karger.com
Osteosarcoma is the most common primary bone malignancy in children and adolescents.
Although improvements in therapeutic strategies were achieved, the outcome remains poor …

[HTML][HTML] NEAT1 upregulates EGCG-induced CTR1 to enhance cisplatin sensitivity in lung cancer cells

P Jiang, X Wu, X Wang, W Huang, Q Feng - Oncotarget, 2016 - ncbi.nlm.nih.gov
Platinum-based drugs are the firstline of treatment for non-small cell lung cancer (NSCLC),
but resistance to these drugs is a major obstacle to effective chemotherapy. Our previous …

Upregulation of the lncRNA MEG3 improves cognitive impairment, alleviates neuronal damage, and inhibits activation of astrocytes in hippocampus tissues in …

J Yi, B Chen, X Yao, Y Lei, F Ou… - Journal of cellular …, 2019 - Wiley Online Library
Objective The purpose of this study was to elucidate the expression of the long noncoding
RNA (lncRNA) maternally expressed gene 3 (MEG3) in rats with Alzheimer's disease (AD) …

Knockdown of lncRNA-XIST enhances the chemosensitivity of NSCLC cells via suppression of autophagy

W Sun, Y Zu, X Fu, Y Deng - Oncology reports, 2017 - spandidos-publications.com
Drug resistance is the major factor contributing to the failure of chemotherapy in non-small
cell lung cancer (NSCLC) patients. Emerging evidence suggests that autophagy plays a vital …

[PDF][PDF] Identification of key long non-coding RNAs as competing endogenous RNAs for miRNA-mRNA in lung adenocarcinoma.

DS Li, JL Ainiwaer, I Sheyhiding… - European Review for …, 2016 - europeanreview.org
OBJECTIVE: RNA-seq data and miRNA-seq data of lung adenocarcinoma (LUAD) were
analyzed to identify critical long non-coding RNAs (lncRNAs) and disclose molecular …

Long non-coding RNAs and their roles in non-small-cell lung cancer

MM Wei, GB Zhou - Genomics, Proteomics and Bioinformatics, 2016 - academic.oup.com
As a leading cause of cancer deaths worldwide, lung cancer is a collection of diseases with
diverse etiologies which can be broadly classified into small-cell lung cancer (SCLC) and …