Blood orange juice intake modulates plasma and PBMC microRNA expression in overweight and insulin-resistant women: impact on MAPK and NFκB signaling …

VC Capetini, BJ Quintanilha, DC de Oliveira… - The Journal of …, 2023 - Elsevier
Blood orange consumption presents potential health benefits and may modulate epigenetic
mechanisms such as microRNAs (miRNAs) expression. MiRNAs are non-coding RNAs …

LncRNA XIST promotes human lung adenocarcinoma cells to cisplatin resistance via let-7i/BAG-1 axis

J Sun, LM Pan, L Chen, Y Wang - Cell Cycle, 2017 - Taylor & Francis
Long noncoding RNAs (lncRNAs) have been identified as oncogenes or tumor suppressors
that are involved in tumorigenesis and chemoresistance. LncRNA XIST expression is …

Silencing long non-coding RNA ROR improves sensitivity of non-small-cell lung cancer to cisplatin resistance by inhibiting PI3K/Akt/mTOR signaling pathway

H Shi, J Pu, XL Zhou, YY Ning, C Bai - Tumor Biology, 2017 - journals.sagepub.com
This study aimed to investigate the effects of long non-coding RNA ROR (regulator of
reprogramming) on cisplatin (DDP) resistance in patients with non-small-cell lung cancer by …

[HTML][HTML] Gemcitabine treatment causes resistance and malignancy of pancreatic cancer stem‑like cells via induction of lncRNA HOTAIR

L Wang, P Dong, W Wang… - Experimental and …, 2017 - spandidos-publications.com
Gemcitabine is the first‑line chemotherapeutic agent for advanced adenocarcinoma of the
pancreas, despite the high risk of chemoresistance as a major disadvantage. In the past few …

The functional role of long noncoding RNA in resistance to anticancer treatment

Y Qu, HY Tan, YT Chan, H Jiang… - … advances in medical …, 2020 - journals.sagepub.com
Chemotherapy is one of the fundamental methods of cancer treatment. However, drug
resistance remains the main cause of clinical treatment failure. We comprehensively review …

[HTML][HTML] Association between well-characterized lung cancer lncRNA polymorphisms and platinum-based chemotherapy toxicity in Chinese patients with lung cancer

W Gong, J Peng, J Yin, X Li, W Zheng, L Xiao… - Acta Pharmacologica …, 2017 - nature.com
Platinum-based chemotherapy is the standard first-line treatment for most lung cancer
patients. However, the toxicity induced by platinum-based chemotherapy greatly impedes its …

Long non-coding RNA MEG3 induces renal cell carcinoma cells apoptosis by activating the mitochondrial pathway

M Wang, T Huang, G Luo, C Huang, X Xiao… - Journal of Huazhong …, 2015 - Springer
This study aimed to examine the effect of long non-coding RNA (LncRNA) MEG3 on the
biological behaviors of renal cell carcinoma (RCC) cells 786-0 and the possible mechanism …

[HTML][HTML] Targeting DNA damage response in the radio (chemo) therapy of non-small cell lung cancer

L Li, T Zhu, YF Gao, W Zheng, CJ Wang, L Xiao… - International journal of …, 2016 - mdpi.com
Lung cancer is the leading cause of cancer death worldwide due to its high incidence and
mortality. As the most common lung cancer, non-small cell lung cancer (NSCLC) is a terrible …

Long noncoding and circular RNAs in lung cancer: advances and perspectives

W Xie, S Yuan, Z Sun, Y Li - Epigenomics, 2016 - Taylor & Francis
Better understanding and management of lung cancer are needed. Although much has
been learned from known protein coding genes, long noncoding RNAs (lncRNAs), a …

[HTML][HTML] Long noncoding RNA CRNDE/PRC2 participated in the radiotherapy resistance of human lung adenocarcinoma through targeting p21 expression

M Zhang, Y Yang, G Li, J Dong, Y Ai, N Chen… - Oncology …, 2018 - ncbi.nlm.nih.gov
Long noncoding RNAs (lncRNAs), a new class of functional regulators involved in human
tumorigenesis, have been attracting the increasing attention of researchers. The lncRNA …