Aside from inheriting half of the genome of each of our parents, we are born with a small
number of novel mutations that occurred during gametogenesis and postzygotically. Recent …

Abstract In December 1997, the National Cancer Institute sponsored “The International
Workshop on Microsatellite Instability and RER Phenotypes in Cancer Detection and …

Autism spectrum disorder (ASD) is an early-onset developmental disorder characterized by
deficits in communication and social interaction and restrictive or repetitive behaviours …

The contribution of repetitive elements to quantitative human traits is largely unknown. Here
we report a genome-wide survey of the contribution of short tandem repeats (STRs), which …

Few genetic markers, if any, have found such widespread use as microsatellites, or
simple/short tandem repeats. Features such as hypervariability and ubiquitous occurrence …

A new measure of the extent of population subdivision as inferred from allele frequencies at
microsatellite loci is proposed and tested with computer simulations. This measure, called R …

Bioresponsive polymers have been widely used in drug delivery because of their
degradability. For example, poly (disulfide) s with repeating disulfide bonds in the main …

We demonstrate that the mean ratio of the number of alleles to the range in allele size, which
we term M, calculated from a population sample of microsatellite loci, can be used to detect …

Genotype-to-phenotype mapping commonly focuses on two major classes of mutations:
single nucleotide polymorphisms (SNPs) and copy number variation (CNV). Here, we …

H istory sometimes takes ironical twists, and the history of science is no exception.
Microsatellites have been detected in eukaryote genomes for over 15 years, though they …