[PDF][PDF] Computational pan-genomics: status, promises and challenges

Briefings in bioinformatics, 2018 - academic.oup.com
Many disciplines, from human genetics and oncology to plant breeding, microbiology and
virology, commonly face the challenge of analyzing rapidly increasing numbers of genomes …

[HTML][HTML] The impact of third generation genomic technologies on plant genome assembly

WB Jiao, K Schneeberger - Current opinion in plant biology, 2017 - Elsevier
Highlights•Plant genomes are more repetitive and complicate to assemble than
vertebrates.•Long-read assembly contigs outperform short-read assembly scaffolds.•Long …

InterPro in 2019: improving coverage, classification and access to protein sequence annotations

AL Mitchell, TK Attwood, PC Babbitt… - Nucleic acids …, 2019 - academic.oup.com
Abstract The InterPro database (http://www. ebi. ac. uk/interpro/) classifies protein
sequences into families and predicts the presence of functionally important domains and …

Rfam 13.0: shifting to a genome-centric resource for non-coding RNA families

I Kalvari, J Argasinska, N Quinones-Olvera… - Nucleic acids …, 2018 - academic.oup.com
The Rfam database is a collection of RNA families in which each family is represented by a
multiple sequence alignment, a consensus secondary structure, and a covariance model. In …

[HTML][HTML] Multiscale analysis of independent Alzheimer's cohorts finds disruption of molecular, genetic, and clinical networks by human herpesvirus

B Readhead, JV Haure-Mirande, CC Funk… - Neuron, 2018 - cell.com
Investigators have long suspected that pathogenic microbes might contribute to the onset
and progression of Alzheimer's disease (AD) although definitive evidence has not been …

InterPro in 2017—beyond protein family and domain annotations

RD Finn, TK Attwood, PC Babbitt… - Nucleic acids …, 2017 - academic.oup.com
Abstract InterPro (http://www. ebi. ac. uk/interpro/) is a freely available database used to
classify protein sequences into families and to predict the presence of important domains …

PLAZA 4.0: an integrative resource for functional, evolutionary and comparative plant genomics

M Van Bel, T Diels, E Vancaester, L Kreft… - Nucleic acids …, 2018 - academic.oup.com
Abstract PLAZA (https://bioinformatics. psb. ugent. be/plaza) is a plant-oriented online
resource for comparative, evolutionary and functional genomics. The PLAZA platform …

Expression Atlas: gene and protein expression across multiple studies and organisms

I Papatheodorou, NA Fonseca, M Keays… - Nucleic acids …, 2018 - academic.oup.com
Abstract Expression Atlas (http://www. ebi. ac. uk/gxa) is an added value database that
provides information about gene and protein expression in different species and contexts …

IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria

A Nakajima, A Vogelzang, M Maruya… - Journal of Experimental …, 2018 - rupress.org
Immunoglobulin A (IgA) promotes health by regulating the composition and function of gut
microbiota, but the molecular requirements for such homeostatic IgA function remain …

A comprehensive and dated phylogenomic analysis of butterflies

M Espeland, J Breinholt, KR Willmott, AD Warren… - Current Biology, 2018 - cell.com
Summary Butterflies (Papilionoidea), with over 18,000 described species [1], have
captivated naturalists and scientists for centuries. They play a central role in the study of …