Considerable progress has been made in recent years in the structural and molecular
biology of type IV secretion systems in Gram-negative bacteria. The latest advances have …

Type IV secretion systems (T4SSs) are versatile multiprotein nanomachines spanning the
entire cell envelope in Gram‐negative and Gram‐positive bacteria. They play important …

HUH endonucleases are numerous and widespread in all three domains of life. The major
function of these enzymes is processing a range of mobile genetic elements by catalysing …

Genetic exchange by conjugation is responsible for the spread of resistance, virulence, and
social traits among prokaryotes. Recent works unraveled the functioning of the underlying …

The bacterial type IV secretion systems (T4SSs) comprise a biologically diverse group of
translocation systems functioning to deliver DNA or protein substrates from donor to target …

Type IV secretion occurs across a wide range of prokaryotic cell envelopes: Gram-negative,
Gram-positive, cell wall-less bacteria and some archaea. This diversity is reflected in the …

Genetic transformation of host plants by Agrobacterium tumefaciens and related species
represents a unique model for natural horizontal gene transfer. Almost five decades of …

Helicobacter pylori (H. pylori) is the strongest identified risk factor for gastric cancer, the third
most common cause of cancer-related death worldwide. An H. pylori constituent that …

Conjugation, the process by which plasmid DNA is transferred from one bacterium to
another, is mediated by type IV secretion systems (T4SSs). T4SSs are versatile systems that …

Historically, the members of the Agrobacterium genus have been considered the only
bacterial species naturally able to transfer and integrate DNA into the genomes of their …