Background Feminizing and masculinizing hormone treatments are established components
of management in transgender patients. Exogenous hormones have been associated with …

Findings from the Women's Health Initiative (WHI) randomised placebo-controlled trial (RCT)
were published at the beginning of this century. They suggested that hormone replacement …

Background Low serum estradiol in early pregnancy is associated with an elevated risk of
miscarriage. We sought to determine whether efforts to restore low blood estradiol via …

Background The aim of this study was to investigate the effect of isopsoralen on osteogenic
differentiation of human jawbone marrow mesenchymal cells and its possible mechanism …

Purpose In adults and children, transsphenoidal surgery (TSS) represents the cornerstone of
management for most large or functioning sellar lesions with the exception of prolactinomas …

Background High estradiol (E 2) levels are linked to an increased risk of venous
thromboembolism; however, the underlying molecular mechanism (s) remain poorly …

Objective Inequity of access and choice to different hormone replacement therapy (HRT)
products across the UK has been suggested (Hillman, 2020). While, the cause is not entirely …

Hemostatic complications are commonly encountered in blood or marrow transplantation
(BMT) recipients, increasing their morbidity and mortality and are well described in the …

STUDY QUESTIONS The primary objective is to investigate if continuous use of oral
contraceptives is non-inferior compared to long-term pituitary desensitization with a GnRH …

Deep vein thrombosis (DVT) commonly develops in the deep veins of the legs, but it can
potentially form in any part of the body. There are several risk factors associated with DVT …