[HTML][HTML] Mitochondrial dysfunction in kidney injury, inflammation, and disease: Potential therapeutic approaches
D Bhatia, A Capili, ME Choi - Kidney research and clinical practice, 2020 - ncbi.nlm.nih.gov
Mitochondria are energy-producing organelles that not only satisfy the high metabolic
demands of the kidney but sense and respond to kidney injury-induced oxidative stress and …
demands of the kidney but sense and respond to kidney injury-induced oxidative stress and …
Circular RNA in renal diseases
J Jin, H Sun, C Shi, H Yang, Y Wu, W Li… - Journal of cellular …, 2020 - Wiley Online Library
Circular RNA (circRNA) is a newly described type of non‐coding RNA. Active research is
greatly enriching the current understanding of the expression and role of circRNA, and a …
greatly enriching the current understanding of the expression and role of circRNA, and a …
ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule
D Liu, G Shu, F Jin, J Qi, X Xu, Y Du, H Yu, J Wang… - Science …, 2020 - science.org
The development of drugs with rapid distribution in the kidney and long-term retention in the
renal tubule is a breakthrough for enhanced treatment of acute kidney injury (AKI). Here, l …
renal tubule is a breakthrough for enhanced treatment of acute kidney injury (AKI). Here, l …
Reversing acute kidney injury through coordinated interplay of anti‐inflammation and iron supplementation
R Duan, Y Li, R Zhang, X Hu, Y Wang… - Advanced …, 2023 - Wiley Online Library
Acute kidney injury (AKI) induced by ischemia reperfusion is closely related to mitochondrial
dysfunction. Nicotinamide adenine dinucleotide (NAD+) can enhance the mitochondrial …
dysfunction. Nicotinamide adenine dinucleotide (NAD+) can enhance the mitochondrial …
Involvement of GPX4 in irisin's protection against ischemia reperfusion‐induced acute kidney injury
J Zhang, J Bi, Y Ren, Z Du, T Li, T Wang… - Journal of Cellular …, 2021 - Wiley Online Library
Abstract Ischemia reperfusion (I/R)‐induced acute kidney injury (AKI) is a common and
serious condition. Irisin, an exercise‐induced hormone, improves mitochondrial function and …
serious condition. Irisin, an exercise‐induced hormone, improves mitochondrial function and …
[HTML][HTML] Effects and molecular mechanism of pachymic acid on ferroptosis in renal ischemia reperfusion injury
GP Jiang, YJ Liao, LL Huang… - Molecular Medicine …, 2021 - spandidos-publications.com
Acute kidney injury (AKI) is a common clinical disease. Ferropotosis, a new type of
regulatory cell death, serves an important regulatory role in AKI. Pachymic acid (PA), a …
regulatory cell death, serves an important regulatory role in AKI. Pachymic acid (PA), a …
Interpretable and context-free deconvolution of multi-scale whole transcriptomic data with UniCell deconvolve
D Charytonowicz, R Brody, R Sebra - Nature communications, 2023 - nature.com
Abstract We introduce UniCell: Deconvolve Base (UCDBase), a pre-trained, interpretable,
deep learning model to deconvolve cell type fractions and predict cell identity across Spatial …
deep learning model to deconvolve cell type fractions and predict cell identity across Spatial …
Exosome-based delivery of super-repressor IκBα ameliorates kidney ischemia-reperfusion injury
Ischemia-reperfusion injury is a major cause of acute kidney injury. Recent studies on the
pathophysiology of ischemia-reperfusion-induced acute kidney injury showed that …
pathophysiology of ischemia-reperfusion-induced acute kidney injury showed that …
Fatal outcomes of COVID-19 in patients with severe acute kidney injury
The outcome of coronavirus disease 2019 (COVID-19) is associated with organ damage;
however, the information about the relationship between acute kidney injury (AKI) and …
however, the information about the relationship between acute kidney injury (AKI) and …
A DNA nanoraft-based cytokine delivery platform for alleviation of acute kidney injury
W Li, C Wang, H Lv, Z Wang, M Zhao, S Liu, L Gou… - Acs Nano, 2021 - ACS Publications
Cytokine immunotherapy represents an attractive strategy to stimulate robust immune
responses for renal injury repair in ischemic acute kidney injury (AKI). However, its clinical …
responses for renal injury repair in ischemic acute kidney injury (AKI). However, its clinical …