Illicit drug use disorders are the most stigmatised health conditions worldwide, and stigma
acts as a meaningful barrier to treatment entry and treatment provision. In the context of …

Importance More than 42 000 Americans died of opioid overdoses in 2016, and the fatalities
continue to increase. This review analyzes the factors that triggered the opioid crisis and its …

This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

Importance Mortality among people with opioid dependence is higher than that of the
general population. Opioid agonist treatment (OAT) is an effective treatment for opioid …

Abstract Background The United States (US) is experiencing an ongoing opioid crisis.
Economic burden estimates that describe the impact of the crisis are needed when …

Importance Medication for opioid use disorder (MOUD) is the criterion standard treatment for
opioid use disorder (OUD), but nationally representative studies of MOUD use in the US are …

Background: Opioid overdose survivors have an increased risk for death. Whether use of
medications for opioid use disorder (MOUD) after overdose is associated with mortality is not …

We summarise the evidence for medicinal uses of opioids, harms related to the extramedical
use of, and dependence on, these drugs, and a wide range of interventions used to address …

Background Alcohol and drug use can have negative consequences on the health,
economy, productivity, and social aspects of communities. We aimed to use data from the …

The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …