[HTML][HTML] Feasibility of using monocyte-derived dendritic cells obtained from cryopreserved cells for DC-based vaccines
L Usero, L Miralles, I Esteban… - Journal of …, 2021 - Elsevier
The study of the effect of cryopreservation on the functionality of monocyte-derived dendritic
cells (MDDCs) and dendritic cells (DCs) is essential for their use in different clinical …
cells (MDDCs) and dendritic cells (DCs) is essential for their use in different clinical …
[HTML][HTML] Abnormally primed CD8 T cells: The Achilles' heel of CHB
X Chen, X Liu, Y Jiang, N Xia, C Liu, W Luo - Frontiers in Immunology, 2023 - frontiersin.org
Chronic hepatitis B virus (HBV) infection continues to be a significant public health
challenge, and more than 250 million people around world are infected with HBV. The …
challenge, and more than 250 million people around world are infected with HBV. The …
Knockout of P2Y12 aggravates experimental autoimmune encephalomyelitis in mice via increasing of IL-23 production and Th17 cell differentiation by dendritic cells
Experimental autoimmune encephalomyelitis (EAE), a common model of multiple sclerosis
(MS), is mainly mediated by CD4+ T cells with demyelination and neurodegeneration of …
(MS), is mainly mediated by CD4+ T cells with demyelination and neurodegeneration of …
[HTML][HTML] Mature dendritic cell derived from cryopreserved immature dendritic cell shows impaired homing ability and reduced anti-viral therapeutic effects
Q Zhou, Y Zhang, M Zhao, X Wang, C Ma, X Jiang… - Scientific reports, 2016 - nature.com
Cryopreservation is critical in reducing redundant operations and also in quality control in
dendritic cell (DC) therapy. Full maturation and efficient homing of DCs to T cell-region …
dendritic cell (DC) therapy. Full maturation and efficient homing of DCs to T cell-region …
How to achieve immune control in chronic hepatitis B?
MJH van Campenhout, HLA Janssen - Hepatology international, 2015 - Springer
Chronic hepatitis B infection remains a major global health problem despite the existence of
an effective vaccine. The current treatment options are either nucleos (t) ide analog therapy …
an effective vaccine. The current treatment options are either nucleos (t) ide analog therapy …
Lentiviral vector encoding ubiquitinated hepatitis B core antigen induces potent cellular immune responses and therapeutic immunity in HBV transgenic mice
S Dai, M Zhuo, L Song, X Chen, Y Yu, G Zang, Z Tang - Immunobiology, 2016 - Elsevier
Predominant T helper cell type 1 (Th1) immune responses accompanied by boosted HBV-
specific cytotoxic T lymphocyte (CTL) activity are essential for the clearance of hepatitis B …
specific cytotoxic T lymphocyte (CTL) activity are essential for the clearance of hepatitis B …
P2Y6 Deficiency Enhances Dendritic Cell–Mediated Th1/Th17 Differentiation and Aggravates Experimental Autoimmune Encephalomyelitis
Dendritic cells (DCs) are essential APCs and play a crucial role in initiating and regulating
the adaptive immune response. In this study, we have reported that P2Y 6, a member of G …
the adaptive immune response. In this study, we have reported that P2Y 6, a member of G …
[HTML][HTML] An engineered DC-targeting lentivector induces robust T cell responses and inhibits HBV replication in HBV transgenic mice via upregulating T cell …
S Ma, X Chen, Q Tan, S Dai, D Li, S Wu, Y Yu… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Developing engineered dendritic cell (DC)-targeting lentivectors (LVs)
have been the target of intense research for their potential to create antigen-directed …
have been the target of intense research for their potential to create antigen-directed …
[HTML][HTML] Immethridine, histamine H3-receptor (H3R) agonist, alleviated experimental autoimmune encephalomyelitis via inhibiting the function of dendritic cells
Multiple sclerosis (MS) is an inflammatory disease that is characterized by immune-
mediated demyelination and degeneration of the central nervous system (CNS) …
mediated demyelination and degeneration of the central nervous system (CNS) …
An engineered novel lentivector specifically transducing dendritic cells and eliciting robust HBV-specific CTL response by upregulating autophagy in T cells
S Ma, X Chen, Q Tan, D Li, S Dai, S Wu, Y Yu, G Zang… - Cell Cycle, 2018 - Taylor & Francis
Dendritic cells (DCs) play a predominant role in initiating cell immune responses. Here we
generated a DC-targeting lentiviral vector (LVDC-UbHBcAg-LIGHT) and evaluated its …
generated a DC-targeting lentiviral vector (LVDC-UbHBcAg-LIGHT) and evaluated its …