The ease of tailoring DNA nanostructures with sub‐nanometer precision has enabled new
and exciting in vivo applications in the areas of chemical sensing, imaging, and gene …

Cellular form and function emerge from complex mechanochemical systems within the
cytoplasm. Currently, no systematic strategy exists to infer large-scale physical properties of …

New findings unravel novel mechanotransduction pathways and effector functions in
platelets, establishing mechanobiology as a pivotal component of platelet function. These …

Immune cells are highly dynamic and able to migrate through environments with diverse
biochemical and mechanical compositions. Their migration has classically been defined as …

The cadherin-catenin complex at adherens junctions (AJs) is essential for the formation of
cell-cell adhesion and epithelium integrity; however, studying the dynamic regulation of AJs …

Blood platelets are central elements of the blood clotting response after wounding. Upon
vessel damage, they bind to the surrounding matrix and contract the forming thrombus, thus …

Measuring the traction forces produced by cells provides insight into their behavior and
physiological function. Here, we developed a technique (dubbed 'black dots') that …

Adherent cells use actomyosin contractility to generate mechanical force and to sense the
physical properties of their environment, with dramatic consequences for migration, division …

We investigate the mechanical interplay between the spatial organization of the actin
cytoskeleton and the shape of animal cells adhering on micropillar arrays. Using a …

Essential cellular processes such as cell adhesion, migration and division strongly depend
on mechanical forces. The standard method to measure cell forces is traction force …