Flipper probes have been introduced as small molecule fluorophores to image physical
forces, that is, membrane tension in living systems. Their emergence over one decade is …

The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …

Exosome analysis is a promising tool for clinical and biological research applications.
However, detection and biomarker quantification of exosomes is technically challenging …

Viscosity is a key characteristic of lipid membranes–it governs the passive diffusion of
solutes and affects the lipid raft formation and membrane fluidity. Precise determination of …

HydroFlippers are introduced as the first fluorescent membrane tension probes that report
simultaneously on membrane compression and hydration. The probe design is centered …

Progress with fluorescent flippers, small-molecule probes to image membrane tension in
living systems, has been limited by the effort needed to synthesize the twisted push–pull …

Cells are responsive to the mechanical environment, but the methods to detect
simultaneously how different organelles react in mechanobiological processes remain …

Lipid peroxidation is a process which is key in cell signaling and disease, it is exploited in
cancer therapy in the form of photodynamic therapy. The appearance of hydrophilic moieties …

Although liquid–liquid phase separation of cytoplasmic or nuclear components in cells has
been a major focus in cell biology, it is only recently that the principle of phase separation …

Lipid order in the cytoplasm membrane of eukaryotic cells undergoes dynamic changes in
almost all cellular processes. Dynamically monitoring these changes is of essential …