Luteolin inhibits Cr (VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways

P Pratheeshkumar, YO Son, SP Divya, RV Roy… - Toxicology and applied …, 2014 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is a well-known human carcinogen associated with
the incidence of lung cancer. Inhibition of metal induced carcinogenesis by a dietary …

Redox‐responsive dual drug delivery nanosystem suppresses cancer repopulation by abrogating doxorubicin‐promoted cancer stemness, metastasis, and drug …

J Liu, B Chang, Q Li, L Xu, X Liu, G Wang… - Advanced …, 2019 - Wiley Online Library
Chemotherapy is a major therapeutic option for cancer patients. However, its effectiveness is
challenged by chemodrugs' intrinsic pathological interactions with residual cancer cells …

[HTML][HTML] Effects of microenvironment in osteosarcoma on chemoresistance and the promise of immunotherapy as an osteosarcoma therapeutic modality

L Yu, J Zhang, Y Li - Frontiers in immunology, 2022 - frontiersin.org
Osteosarcoma (OS) is one of the most common primary malignant tumors originating in
bones. Its high malignancy typically manifests in lung metastasis leading to high mortality …

[HTML][HTML] Mechanistic and pharmacological issues of aspirin as an anticancer agent

M Dovizio, S Tacconelli, C Sostres, E Ricciotti… - Pharmaceuticals, 2012 - mdpi.com
Recent findings have shown that aspirin, taken for several years, reduces the long-term risk
of some cancers, particularly colorectal cancer. The result that aspirin benefit is detectable at …

Chemoprevention of colorectal neoplasia: the potential for personalized medicine

N Arber, B Levin - Gastroenterology, 2008 - Elsevier
CRC development is a multi-step process that spans 10 to 15 years, thereby providing an
opportunity for early detection and even prevention. The poor survival rate of advanced CRC …

中国大肠肿瘤筛查, 早诊早治和综合预防共识意见

房静远 - 胃肠病学和肝病学杂志, 2011 - cqvip.com
大肠癌(即结直肠癌, Colorectalcancer, CRC) 是我国常见的恶性肿瘤. 在西方发达国家其发病率
居恶性肿瘤的第2-3 位. 随着国人生活水平的不断提高和饮食习惯的变化 …

Pilot randomized phase II study of celecoxib in oral premalignant lesions

VA Papadimitrakopoulou, WN William Jr… - Clinical Cancer …, 2008 - AACR
Abstract Purpose: Cyclooxygenase-2 (COX-2)–specific inhibition suppresses
carcinogenesis in preclinical models and is a promising strategy for preventing oral cancer …

Structural alterations based on naproxen scaffold: Synthesis, evaluation of antitumor activity and COX-2 inhibition, and molecular docking

WM El-Husseiny, AA Magda, NI Abdel-Aziz… - European journal of …, 2018 - Elsevier
A new series of non-carboxylic naproxen analogues, bearing a variety of ring systems, such
as oxadiazoles 3a–c and 6a–c, cycloalkanes 4a–d, cyclic imides 5a–c, and triazoles 7–9 …

Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy

E Naschberger, RS Croner, S Merkel… - … journal of cancer, 2008 - Wiley Online Library
Angiogenesis and inflammation are the 2 major stroma reactions in colorectal carcinoma
(CRC). Guanylate binding protein‐1 (GBP‐1) is a key mediator of angiostatic effects of …

Chemoprevention of oral cancer: A review and future perspectives

YH Liao, WY Chou, CW Chang, MC Lin… - Head & …, 2023 - Wiley Online Library
Background Oral cancer causes significant morbidity and mortality. Chemoprevention
utilizes medication or natural compounds to reverse oral premalignant lesions and to …