The limited success of current treatments for most advanced common malignancies
highlights the importance of cancer prevention. Clinical trials on cyclooxygenase (COX) …

Background Increasing the efficacy of chemotherapeutics by reducing chemoresistance may
be a useful strategy in cancer therapy. Constitutive activation of nuclear factor-kappa B (NF …

There is growing interest in dietary phytochemicals as potential cancer chemopreventive
agents. Resveratrol (3, 4′, 5-trihydroxy-trans-stilbene), a naturally occurring phytoalexin …

Visceral obesity is characterized by increased risk of cardiovascular disease as well as
higher incidence of malignancies, including colorectal cancer (CRC), although the …

The present study investigated the preventive effects of etodolac, a selective cyclo‐
oxygenase (COX)‐2 inhibitor, on metachronous cancer development after endoscopic …

Background and aims Early detection and treatment of human colorectal cancers remain a
challenge. Identification of new potential markers may help in the diagnosis of colorectal …

A large body of evidence from basic science, epidemiologic observations and population-
based studies demonstrates that aspirin, as well as other non-steroidal anti-inflammatory …

Background: Colorectal cancer (CRC) is steadily increasing in China. Colorectal adenoma
(CRA) is the most important precancerous disease of CRC. Screening for colorectal tumors …

Purpose: Cyclic hypoxia in tumors originates from heterogeneities in RBC flux and
influences not only tumor cells but also endothelial cells lining tumor blood vessels. Whether …

Inflammation and subsequent cyclooxygenase-2 (COX-2) activity has long been linked with
the development of cancer, although little is known about any epigenetic effects of COX-2. A …