Obesity and central adiposity are associated with colorectal cancer risk and have been
linked to inflammation. Inflammation is a complex, interactive response that may most …

The inducible prostaglandin synthase isoform cyclooxygenase-2 (COX-2) is overexpressed
in∼ 40% of human breast carcinomas and in precancerous breast lesions, particularly in …

Anti-inflammatory drugs prevent intestinal tumor formation, an activity related to their ability
to inhibit inflammatory pathway signaling in the target tissue. We previously showed that …

Abstract Cyclooxygenase-2 (COX-2) is a key regulator of inflammation. High constitutive
COX-2 expression enhances survival and proliferation of cancer cells, and adversely …

Role of chronic inflammation in cancers of the gastrointestinal system and the liver: where we are
now Role of chronic inflammation in cancers of the gastrointestinal system and the liver: where …

Observational studies have been largely consistent in showing an inverse association
between vitamin D and an individual's risk of developing colorectal cancer. Vitamin D …

Background & Aims Cyclooxygenase-2 (COX-2) is known to promote the carcinogenesis of
esophageal squamous cell carcinoma (ESCC). There are no reports on whether microRNAs …

Oral squamous cell carcinoma (OSCC) is a group of highly malignant tumors that may arise
from the surface epithelium or minor salivary glands. Approximately 85% to 95% of all oral …

The esophageal anatomy from a surgical standpoint is fairly simple; however, an
understanding of particular intricacies is essential to ensuring a successful outcome with …

Aspirin is the best chemoprevention agent for colorectal cancer risk reduction despite the
fact that the evidence for a decrease in mortality is weak. The cyclooxygenase-2 selective …