[HTML][HTML] Thromboembolic adverse drug reactions in Janus kinase (JAK) inhibitors: does the inhibitor specificity play a role?

PJ Kotyla, M Engelmann, J Giemza-Stokłosa… - International journal of …, 2021 - mdpi.com
Recent advances in immunology enabled the characterization of several signal transmitting
pathways responsible for proper cytokine and chemokine signaling. Among them, Janus …

[HTML][HTML] Therapy development by genome editing of hematopoietic stem cells

L Koniali, CW Lederer, M Kleanthous - Cells, 2021 - mdpi.com
Accessibility of hematopoietic stem cells (HSCs) for the manipulation and repopulation of the
blood and immune systems has placed them at the forefront of cell and gene therapy …

[HTML][HTML] Etiologic subtypes of ischemic stroke in SARS-CoV-2 patients in a cohort of New York City hospitals

A Tiwari, K Berekashvili, V Vulkanov, S Agarwal… - Frontiers in …, 2020 - frontiersin.org
Objective: To describe the ischemic stroke subtypes related to coronavirus disease 2019
(COVID-19) in a cohort of New York City hospitals and explore their etiopathogenesis …

[HTML][HTML] Using innovative machine learning methods to screen and identify predictors of congenital heart diseases

Y Qu, X Deng, S Lin, F Han, HH Chang, Y Ou… - Frontiers in …, 2022 - frontiersin.org
Objective: Congenital heart diseases (CHDs) are associated with an extremely heavy global
disease burden as the most common category of birth defects. Genetic and environmental …

Comparison of hemodynamic features and thrombosis risk of membrane oxygenators with different structures: A numerical study

X Fu, Z Su, Y Wang, A Sun, L Wang, X Deng… - Computers in Biology …, 2023 - Elsevier
Purpose The geometric structure of the membrane oxygenator can exert an impact on its
hemodynamic features, which contribute to the development of thrombosis, thereby affecting …

Acute myocardial infarction: etiologies and mimickers in young patients

C Krittanawong, M Khawaja… - Journal of the …, 2023 - Am Heart Assoc
Acute myocardial infarction is an important cause of death worldwide. While it often affects
patients of older age, acute myocardial infarction is garnering more attention as a significant …

[HTML][HTML] Identification and characterization of two SERPINC1 mutations causing congenital antithrombin deficiency

H Wang, D Ruan, M Wu, Y Ji, X Hu, Q Wu, Y Zhang… - Thrombosis …, 2023 - Springer
Background Antithrombin (AT) is the main physiological anticoagulant involved in
hemostasis. Hereditary AT deficiency is a rare autosomal dominant thrombotic disease …

[HTML][HTML] Personalized modulation of coagulation factors using a thrombin dynamics model to treat trauma-induced coagulopathy

DE Ghetmiri, MJ Cohen, AA Menezes - npj Systems Biology and …, 2021 - nature.com
Current trauma-induced coagulopathy resuscitation protocols use slow laboratory
measurements, rules-of-thumb, and clinician gestalt to administer large volumes of …

[HTML][HTML] Quick model-based viscoelastic clot strength predictions from blood protein concentrations for cybermedical coagulation control

DE Ghetmiri, AJ Venturi, MJ Cohen… - Nature …, 2024 - nature.com
Cybermedical systems that regulate patient clotting in real time with personalized blood
product delivery will improve treatment outcomes. These systems will harness popular …

Venous Thromboembolism in Total Hip and Total Knee Arthroplasty

SJ Simon, R Patell, JI Zwicker, DS Kazi… - JAMA Network …, 2023 - jamanetwork.com
Importance The optimal pharmacologic thromboprophylaxis agent after total hip and total
knee arthroplasty is uncertain and consensus is lacking. Quantifying the risk of postoperative …