Recent advances in hydrogel based drug delivery systems for the human body
The upsurge in the need of targeted controlled drug delivery (TCDD) has led to the invention
of remarkable biomaterials with improved biocompatibility and biodegradability. In recent …
of remarkable biomaterials with improved biocompatibility and biodegradability. In recent …
Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma
Among central nervous system tumors, Glioblastoma (GBM) is the most common, aggressive
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …
[HTML][HTML] Injectable thermoresponsive hydrogels as drug delivery system for the treatment of central nervous system disorders: A review
The central nervous system (CNS), consisting of the brain, spinal cord, and retina,
superintends to the acquisition, integration and processing of peripheral information to …
superintends to the acquisition, integration and processing of peripheral information to …
[HTML][HTML] Hydrogel-based drug delivery nanosystems for the treatment of brain tumors
Chemotherapy is commonly associated with limited effectiveness and unwanted side effects
in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells …
in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells …
[HTML][HTML] Design of biopolymer-based interstitial therapies for the treatment of glioblastoma
Glioblastoma multiforme (GBM) is the most common form of primary brain cancer and has
the highest morbidity rate and current treatments result in a bleak 5-year survival rate of …
the highest morbidity rate and current treatments result in a bleak 5-year survival rate of …
Enhancement of the fraction of the active form of an antitumor drug topotecan via an injectable hydrogel
G Chang, T Ci, L Yu, J Ding - Journal of controlled release, 2011 - Elsevier
Poly (D, L-lactic acid-co-glycolic acid)-b-poly (ethylene glycol)-b-poly (D, L-lactic acid-co-
glycolic acid)(PLGA–PEG–PLGA) hydrogels were tried as implants to encapsulate antitumor …
glycolic acid)(PLGA–PEG–PLGA) hydrogels were tried as implants to encapsulate antitumor …
Drug encapsulated polymeric microspheres for intracranial tumor therapy: a review of the literature
JA Floyd, A Galperin, BD Ratner - Advanced drug delivery reviews, 2015 - Elsevier
Despite intensive surgical excision, radiation therapy, and chemotherapy, the current life
expectancy for patients diagnosed with glioblastoma multiforme is only 12 to 15 months …
expectancy for patients diagnosed with glioblastoma multiforme is only 12 to 15 months …
Engineered hydrogels for brain tumor culture and therapy
Brain tumors' severity ranges from benign to highly aggressive and invasive. Bioengineering
tools can assist in understanding the pathophysiology of these tumors from outside the body …
tools can assist in understanding the pathophysiology of these tumors from outside the body …
Nanopharmacology in translational hematology and oncology
C Tomuleasa, C Braicu, A Irimie, L Craciun… - International Journal …, 2014 - Taylor & Francis
Nanoparticles have displayed considerable promise for safely delivering therapeutic agents
with miscellaneous therapeutic properties. Current progress in nanotechnology has put …
with miscellaneous therapeutic properties. Current progress in nanotechnology has put …
[HTML][HTML] Biocompatible copolymer formulations to treat glioblastoma multiforme
LCS Erthal, OL Gobbo, E Ruiz-Hernandez - Acta biomaterialia, 2021 - Elsevier
The treatment for glioblastoma multiforme (GBM) has not changed for more than 20 years
while the prognosis for the patients is still poor and most of them survive less than 1 year …
while the prognosis for the patients is still poor and most of them survive less than 1 year …