Objectives: The objectives of this study were to assess comparative effectiveness and harms
of opioid and nonopioid analgesics for the treatment of moderate to severe acute pain in the …

Method: In the present meta-analysis, controlled human studies were included. An extensive
search was conducted in electronic databases including Medline (via PubMed), Embase …

Background Few publications have addressed prehospital use of ketamine in analgesic
doses. We aimed to assess the effect and safety profile of ketamine compared with other …

Study objective To describe out-of-hospital ketamine use, patient outcomes, and the
potential contribution of ketamine to patient death. Methods We retrospectively evaluated …

Hemorrhage is a leading cause of battlefield and civilian trauma deaths. Several pain
medications, including fentanyl, are recommended for use in the prehospital (ie, field setting) …

Hemorrhage is a leading cause of preventable battlefield and civilian trauma deaths.
Ketamine, fentanyl, and morphine are recommended analgesics for use in the prehospital …

Materials and methods This single-center observational study was conducted in the ED of
the Marmara University Pendik Training and Research Hospital between August 2018 and …

This paper is the forty-first consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

We report the initial seven patients treated with nebulized ketamine for moderate to severe
pain, via breath-actuated nebulizer, in an urban, ground-based emergency medical services …

Introduction: With a sharp increase in NSAIDs and opioid use for chronic pain conditions
associated with traumatic injuries and diseases, there has been an escalated risk of life …