Efficacy and safety of nintedanib in patients with idiopathic pulmonary fibrosis who are elderly or have comorbidities

I Glaspole, F Bonella, E Bargagli, MK Glassberg… - Respiratory …, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) predominantly affects individuals aged> 60
years who have several comorbidities. Nintedanib is an approved treatment for IPF, which …

Inositol possesses antifibrotic activity and mitigates pulmonary fibrosis

JM Li, WH Chang, L Li, DC Yang, SW Hsu… - Respiratory …, 2023 - Springer
Background Myo-inositol (or inositol) and its derivatives not only function as important
metabolites for multiple cellular processes but also act as co-factors and second …

Dynapenia is highly prevalent in older patients with advanced idiopathic pulmonary fibrosis

M Bocchino, P Alicante, L Capitelli, AA Stanziola… - Scientific Reports, 2021 - nature.com
Body composition and muscle strength are emerging aspects in idiopathic pulmonary
fibrosis (IPF) clinical assessment. We aimed to study the relationships of handgrip strength …

Clinical impact of weight loss on mortality in patients with idiopathic pulmonary fibrosis: a retrospective cohort study

JK Lee, C Chung, J Kim, HS Cho, HC Kim - Scientific Reports, 2023 - nature.com
Patients with idiopathic pulmonary fibrosis (IPF) often experience weight loss during the
follow-up period. However, the prevalence and clinical impact of weight loss in these …

Nutrition implications of intrinsic restrictive lung disease

S Rinaldi, C Balsillie, C Truchon… - Nutrition in Clinical …, 2022 - Wiley Online Library
Restrictive lung disease is defined as a reduction in lung volume that may be due to
intraparenchymal or extraparenchymal causes. Intraparenchymal causes falls under the …

Integrative analyses for the identification of idiopathic pulmonary fibrosis-associated genes and shared loci with other diseases

M Chen, Y Zhang, T Adams, D Ji, W Jiang, LV Wain… - Thorax, 2023 - thorax.bmj.com
Background Although genome-wide association studies (GWAS) have identified many
genomic regions associated with idiopathic pulmonary fibrosis (IPF), the causal genes and …

The novel molecular mechanism of pulmonary fibrosis: insight into lipid metabolism from reanalysis of single-cell RNA-seq databases

X Shi, Y Chen, M Shi, F Gao, L Huang, W Wang… - Lipids in Health and …, 2024 - Springer
Pulmonary fibrosis (PF) is a severe pulmonary disease with limited available therapeutic
choices. Recent evidence increasingly points to abnormal lipid metabolism as a critical …

I-PreFer study: a questionnaire to explore patient, caregiver and pulmonologist preferences of idiopathic pulmonary fibrosis treatment options

M Hollmen, T Bromilow, AB Smith… - Patient preference …, 2023 - Taylor & Francis
Introduction Idiopathic Pulmonary Fibrosis (IPF) is a rare disease that causes shortness of
breath, dry cough, and tiredness. While there is no cure for IPF, current therapeutic …

Time-dependent propensity-matched general population study of the effects of statin use on cancer risk in an interstitial lung disease and pulmonary fibrosis cohort

JJ Yeh, JN Lai, CL Lin, CY Hsu, CH Kao - BMJ open, 2021 - bmjopen.bmj.com
Objective To determine the effect of statins on risk of cancer in patients with interstitial lung
disease (ILD) and pulmonary fibrosis. Setting We retrospectively enrolled patients with ILD …

Rectus Femoris Cross-Sectional Area and Phase Angle asPredictors of 12-Month Mortality in Idiopathic Pulmonary Fibrosis Patients

R Fernández-Jiménez, E Cabrera Cesar… - Nutrients, 2023 - mdpi.com
Background: The value of the phase angle (PhA), measured via bioelectrical impedance
analysis (BIA), could be considered a good marker of the cell mass and the cell damage of a …