Evidence of central nervous system (CNS) exogenous opioid effects in humans has been
primarily gained through neuroimaging of three participant populations: individuals after …

Background The trauma mortality rate is higher in the elderly compared with younger
patients. Ageing is associated with physiological changes in multiple systems and correlated …

Introduction Proper pain in acute scapular fractures can be challenging to achieve due to
their anatomy and location. While the current mainstay of treatment relies on opioids, the …

For adults with moderate to severe pain in the emergency department (ED), IV
acetaminophen may offer similar levels of pain relief and a similar risk of adverse events as …

Training and expertise in regional anaesthesia have increased significantly in tandem with
increased interest over the past two decades. This review outlines the most recent advances …

Objective This narrative review aims to provide a clinical perspective on the potential role of
co-crystal of tramadol–celecoxib (CTC) in the management of acute moderate-to-severe …

Ketamine is a phencyclidine (PCP) derivative, which primarily acts as a noncompetitive N-
methyl-D-aspartate (NMDA) receptor antagonist. Ketamine serves as an analgesic and a …

Introduction Airway compromise is the second leading cause of potentially preventable
death on the battlefield. Prehospital airway management is often unavoidable in a kinetic …

Background: Burn wound dressing and debridement are excruciatingly painful procedures
that call for appropriate analgesia—typically multimodal. Better post-procedural pain …

Abstract Background In the Emergency Department (ED), patients may present with various
injuries that damage muscles, tendons, ligaments, and bony structures. Fractures, joint …