The management of portal hypertension should be based on an updated knowledge of its
natural history. Portal hypertension is an almost unavoidable complication of cirrhosis, and it …

BACKGROUND & AIMS: Renin–angiotensin–aldosterone antagonists [ACE inhibitors
(ACEi), angiotensin receptor blockers (ARB), aldosterone antagonists (AA)] are potential …

Metabolic processes utilize a variety of differing and contrasting biochemical routes to
enable synthesis of degradation and activation or deactivation of substances; in addition …

Portal hypertension (PHT) is responsible for the more severe and often lethal complications
of cirrhosis such as bleeding oesophageal varices, ascites, renal dysfunction and hepatic …

Background/Aims: To assess the effects of the early and chronic administration of losartan-a
specific angiotensin II receptor antagonist-in the prevention of hepatic fibrosis and portal …

Morbidity and mortality of chronic liver disease are primarily caused by liver cirrhosis and
portal hypertension, both of them secondary disorders of progressive liver fibrosis. The main …

Portal hypertension is an almost unavoidable complication of cirrhosis, and it is responsible
for the more lethal complications of this syndrome: gastro–esophageal varices and massive …

Introduction The development of portal hypertension leads to a majority of complications
associated with chronic liver disease. Therefore, adequate treatment of portal hypertension …

Аннотация Актуальность и необходимость темы диссертации. В настоящее время, по
данным Всемирной организации здравоохранения, полипрагмазия является одной из …

Background Portal hypertension in cirrhosis is the result of increased intrahepatic vascular
resistance to portal outflow as well as increased portal tributary blood flow. The angiotensin …