Mass spectrometry has been the “gold standard” for drugs of abuse (DoA) analysis for many
decades because of the selectivity and sensitivity it affords. Recent progress in all aspects of …

In recent years, the consumption of synthetic cathinones has grown continuously as these
drugs represent a more affordable and obtainable alternative to amphetamines. After …

Pipette tip solid-phase extraction facilitates the handling of low-volume samples and organic
solvents in order to achieve more environmentally friendly pre-treatment sample techniques …

Cocaine (COC) is one of the most widely abused drugs in the world and its sensitive and its
reliable measurement in blood is of great importance in the field of forensic and clinical …

Objective To assess routine application and clinical value of definitive urine drug monitoring
(UDM) for drug detection, inconsistent drug use, and prescription adherence, along with a …

N-ethylhexedrone (NEH) and buphedrone (BUPH) are synthetic drugs structurally related to
natural cathinone. These synthetic cathinones (SC) are members of the heterogenous family …

The constant legal adaptation of new psychoactive substances (NPS), challenges their
evaluation in different fields. In sports, NPS are prohibited in competition with a reporting …

An overview of the detection of benzodiazepines and their respective metabolites and target
analytes in urine by LC-MS/MS is described. This overview shows substantial differences in …

The transition from presumptive (immunoassay) drug screening to definitive screening has
continued in the practice of analytical toxicology. Development of a ultra-performance liquid …

Analytical performance of stable isotope-labeled internal standardization (SIL-IS) and
threshold accurate calibration (TAC) methods of matrix normalization are compared for …