Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019 - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

[HTML][HTML] Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects

KC Sonntag, B Song, N Lee, JH Jung, Y Cha… - Progress in …, 2018 - Elsevier
Parkinson's disease (PD) is one of the most common neurodegenerative disorders, which
affects about 0.3% of the general population. As the population in the developed world ages …

[HTML][HTML] Efficient derivation of transgene-free porcine induced pluripotent stem cells enables in vitro modeling of species-specific developmental timing

JV Conrad, S Meyer, PS Ramesh, JA Neira… - Stem Cell Reports, 2023 - cell.com
Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical
studies because of its comparable physiology and organ size to humans. The derivation of …

Human induced pluripotent stem cells as a platform for personalized and precision cardiovascular medicine

E Matsa, JH Ahrens, JC Wu - Physiological Reviews, 2016 - journals.physiology.org
Human induced pluripotent stem cells (hiPSCs) have revolutionized the field of human
disease modeling, with an enormous potential to serve as paradigm shifting platforms for …

[HTML][HTML] Need for high-resolution genetic analysis in iPSC: results and lessons from the ForIPS consortium

B Popp, M Krumbiegel, J Grosch, A Sommer, S Uebe… - Scientific reports, 2018 - nature.com
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as
disease models and for potential therapeutic use. We describe the comprehensive analysis …

Cell transplantation for spinal cord injury: tumorigenicity of induced pluripotent stem cell‐derived neural stem/progenitor cells

J Deng, Y Zhang, Y Xie, L Zhang… - Stem Cells …, 2018 - Wiley Online Library
Spinal cord injury (SCI) is an intractable and worldwide difficult medical challenge with
limited treatments. Neural stem/progenitor cell (NS/PC) transplantation derived from fetal …

Repurposing the cord blood bank for haplobanking of HLA-homozygous iPSCs and their usefulness to multiple populations

S Lee, JY Huh, DM Turner, S Lee, J Robinson… - Stem …, 2018 - academic.oup.com
Although autologous induced pluripotent stem cells (iPSCs) can potentially be useful for
treating patients without immune rejection, in reality it will be extremely expensive and labor …

Induced Pluripotent Stem Cells: Progress toward Clinical Translation from Bench to Bedside

AOJ Fakoya, AE Omole, N Satyadev… - Handbook of stem cell …, 2022 - Springer
Induced pluripotent stem cells (iPSCs) offer huge promise and potential in the creation of
patient-specific stem cells for modeling human diseases, drug development and testing, and …

[HTML][HTML] Induced pluripotent stem cells: advances in the quest for genetic stability during reprogramming process

V Turinetto, L Orlando, C Giachino - International journal of molecular …, 2017 - mdpi.com
Evaluation of the extent and nature of induced pluripotent stem cell (iPSC) genetic instability
is important for both basic research and future clinical use. As previously demonstrated …