Advanced drug delivery systems and artificial skin grafts for skin wound healing
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …
painstakingly long-term treatment with an immense financial burden to healthcare systems …
[HTML][HTML] Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
M Chehelgerdi, F Behdarvand Dehkordi… - Molecular Cancer, 2023 - Springer
The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …
Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects
Parkinson's disease (PD) is one of the most common neurodegenerative disorders, which
affects about 0.3% of the general population. As the population in the developed world ages …
affects about 0.3% of the general population. As the population in the developed world ages …
[HTML][HTML] Efficient derivation of transgene-free porcine induced pluripotent stem cells enables in vitro modeling of species-specific developmental timing
JV Conrad, S Meyer, PS Ramesh, JA Neira… - Stem Cell Reports, 2023 - cell.com
Sus scrofa domesticus (pig) has served as a superb large mammalian model for biomedical
studies because of its comparable physiology and organ size to humans. The derivation of …
studies because of its comparable physiology and organ size to humans. The derivation of …
Human induced pluripotent stem cells as a platform for personalized and precision cardiovascular medicine
Human induced pluripotent stem cells (hiPSCs) have revolutionized the field of human
disease modeling, with an enormous potential to serve as paradigm shifting platforms for …
disease modeling, with an enormous potential to serve as paradigm shifting platforms for …
[HTML][HTML] Need for high-resolution genetic analysis in iPSC: results and lessons from the ForIPS consortium
B Popp, M Krumbiegel, J Grosch, A Sommer, S Uebe… - Scientific reports, 2018 - nature.com
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as
disease models and for potential therapeutic use. We describe the comprehensive analysis …
disease models and for potential therapeutic use. We describe the comprehensive analysis …
Cell transplantation for spinal cord injury: tumorigenicity of induced pluripotent stem cell‐derived neural stem/progenitor cells
J Deng, Y Zhang, Y Xie, L Zhang… - Stem Cells …, 2018 - Wiley Online Library
Spinal cord injury (SCI) is an intractable and worldwide difficult medical challenge with
limited treatments. Neural stem/progenitor cell (NS/PC) transplantation derived from fetal …
limited treatments. Neural stem/progenitor cell (NS/PC) transplantation derived from fetal …
Repurposing the cord blood bank for haplobanking of HLA-homozygous iPSCs and their usefulness to multiple populations
S Lee, JY Huh, DM Turner, S Lee, J Robinson… - Stem …, 2018 - academic.oup.com
Although autologous induced pluripotent stem cells (iPSCs) can potentially be useful for
treating patients without immune rejection, in reality it will be extremely expensive and labor …
treating patients without immune rejection, in reality it will be extremely expensive and labor …
Induced Pluripotent Stem Cells: Progress toward Clinical Translation from Bench to Bedside
Induced pluripotent stem cells (iPSCs) offer huge promise and potential in the creation of
patient-specific stem cells for modeling human diseases, drug development and testing, and …
patient-specific stem cells for modeling human diseases, drug development and testing, and …
[HTML][HTML] Induced pluripotent stem cells: advances in the quest for genetic stability during reprogramming process
V Turinetto, L Orlando, C Giachino - International journal of molecular …, 2017 - mdpi.com
Evaluation of the extent and nature of induced pluripotent stem cell (iPSC) genetic instability
is important for both basic research and future clinical use. As previously demonstrated …
is important for both basic research and future clinical use. As previously demonstrated …