Alzheimer's disease (AD) is a neurodegenerative disorder that nowadays affects more than
40 million people worldwide and it is predicted to exponentially increase in the coming …

Neurodegenerative diseases (NDDs) are incurable and debilitating conditions that result in
progressive degeneration and/or death of nerve cells in the central nervous system (CNS) …

Although great advances in elucidating the molecular basis and pathogenesis of
Alzheimer's disease (AD) have been made and multifarious novel therapeutic approaches …

The only drugs currently approved for the treatment of Alzheimer's Disease (AD) are four
acetylcholinesterase inhibitors and the NMDA antagonist memantine. Apart from these …

A robust preclinical disease model is a primary requirement to understand the underlying
mechanisms, signaling pathways, and drug screening for human diseases. Although various …

Rationale Chemotherapy-induced cognitive impairment (CICI), chemobrain, and chemofog
are the common terms for mental dysfunction in a cancer patient/survivor under the influence …

Introduction: Memory is defined as the ability to store, maintain and retrieve information.
Learning is the acquisition of information that changes behavior and memory. Stress …

Animal models for learning and memory have significantly contributed to novel strategies for
drug development and hence are an imperative part in the assessment of therapeutics …

Inhibition of Ca 2+ entry into the hippocampus and dorsal root ganglion (DRG) through
inhibition of N-methyl-d-aspartate (NMDA) receptor antagonist drugs is the current standard …

We all know that age-related neurodegenerative diseases affect aging individuals. So why
does basic research continue to make use of the immature nervous system or mutants that …