Toxicity of amphetamines: an update

M Carvalho, H Carmo, VM Costa, JP Capela… - Archives of …, 2012 - Springer
Amphetamines represent a class of psychotropic compounds, widely abused for their
stimulant, euphoric, anorectic, and, in some cases, emphathogenic, entactogenic, and …

Cytokines mediated inflammation and decreased neurogenesis in animal models of depression

C Song, H Wang - Progress in Neuro-Psychopharmacology and …, 2011 - Elsevier
In patients with major depression or in animal models of depression, significantly increases
in the concentrations of pro-inflammatory cytokines have been consistently reported …

Mechanisms of action and persistent neuroplasticity by drugs of abuse

ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - ASPET
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine

T Canedo, CC Portugal, R Socodato… - …, 2021 - nature.com
Methamphetamine (Meth) is a powerful illicit psychostimulant, widely used for recreational
purposes. Besides disrupting the monoaminergic system and promoting oxidative brain …

Amphetamine toxicities: classical and emerging mechanisms

BK Yamamoto, A Moszczynska… - Annals of the New York …, 2010 - Wiley Online Library
The drugs of abuse, methamphetamine and MDMA, produce long‐term decreases in
markers of biogenic amine neurotransmission. These decreases have been traditionally …

Drugs of abuse and blood-brain barrier endothelial dysfunction: A focus on the role of oxidative stress

RK Sajja, S Rahman, L Cucullo - Journal of Cerebral Blood …, 2016 - journals.sagepub.com
Psychostimulants and nicotine are the most widely abused drugs with a detrimental impact
on public health globally. While the long-term neurobehavioral deficits and synaptic …

The effects of psychostimulant drugs on blood brain barrier function and neuroinflammation

SM Kousik, TC Napier, PM Carvey - Frontiers in pharmacology, 2012 - frontiersin.org
The blood brain barrier (BBB) is a highly dynamic interface between the central nervous
system (CNS) and periphery. The BBB is comprised of a number of components and is part …

The ugly side of amphetamines: short- and long-term toxicity of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy'), methamphetamine and d-amphetamine

T Steinkellner, M Freissmuth, HH Sitte, T Montgomery - 2011 - degruyter.com
Abstract Amphetamine ('Speed'), methamphetamine ('Ice') and its congener 3, 4-
methylenedioxymethamphetamine (MDMA;'Ecstasy') are illicit drugs abused worldwide for …

Multifaces of neuropeptide Y in the brain–neuroprotection, neurogenesis and neuroinflammation

JO Malva, S Xapelli, S Baptista, J Valero, F Agasse… - Neuropeptides, 2012 - Elsevier
Neuropeptide Y (NPY) has been implicated in the modulation of important features of
neuronal physiology, including calcium homeostasis, neurotransmitter release and …

Molecular characterisation of the mechanism of action of stimulant drugs lisdexamfetamine and methylphenidate on ADHD neurobiology: a review

J Quintero, JR Gutiérrez-Casares, C Álamo - Neurology and therapy, 2022 - Springer
Attention-deficit/hyperactivity disorder (ADHD) is a common childhood-onset
neurodevelopmental disorder characterised by persistent inattention, hyperactivity and …