[HTML][HTML] Cervical cancer therapies: Current challenges and future perspectives

CA Burmeister, SF Khan, G Schäfer, N Mbatani… - Tumour Virus …, 2022 - Elsevier
Cervical cancer is the fourth most common female cancer worldwide and results in over 300
000 deaths globally. The causative agent of cervical cancer is persistent infection with high …

[HTML][HTML] Involvement of human papillomaviruses in cervical cancer

X Wang, X Huang, Y Zhang - Frontiers in microbiology, 2018 - frontiersin.org
Human papillomaviruses (HPV) are the first viruses to have been acknowledged to prompt
carcinogenesis, and they are linked with cancers of the uterine cervix, anogenital tumors …

[HTML][HTML] Role of IL-10 and TGF-β1 in local immunosuppression in HPV-associated cervical neoplasia

K Torres-Poveda, M Bahena-Román… - World journal of …, 2014 - ncbi.nlm.nih.gov
Cervical cancer is a worldwide disease that constitutes a significant public health problem,
especially in developing countries, not only due to its high incidence but also because the …

Immunotherapy and targeted therapy for cervical cancer: an update

G Menderes, J Black, CL Schwab… - Expert review of …, 2016 - Taylor & Francis
The prognosis of patients with metastatic cervical cancer is poor with a median survival of 8–
13 months. Despite the potency of chemotherapeutic drugs, this treatment is rarely curative …

[HTML][HTML] Human papillomavirus infection, cervical cancer and the less explored role of trace elements

AB Sravani, V Ghate, S Lewis - Biological Trace Element Research, 2023 - Springer
Cervical cancer is an aggressive type of cancer affecting women worldwide. Many affected
individuals rely on smear tests for the diagnosis, surgery, chemotherapy, or radiation for their …

Signaling pathways in HPV‐associated cancers and therapeutic implications

J Chen - Reviews in medical virology, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) are small double‐stranded circular DNA viruses with 8 kb
genomes. So far, more than 150 HPVs have been identified, and 12 types of HPVs have …

[HTML][HTML] hrHPV E5 oncoprotein: immune evasion and related immunotherapies

AC de Freitas, THA de Oliveira, MR Barros… - Journal of Experimental & …, 2017 - Springer
The immune response is a key factor in the fight against HPV infection and related cancers,
and thus, HPV is able to promote immune evasion through the expression of oncogenes. In …

Anticancer activity of selenium nanoparticles in vitro studies

F Martínez-Esquivias… - Anti-Cancer Agents …, 2022 - ingentaconnect.com
Health systems worldwide consider cancer a disease that causes the highest number of
deaths per year. The low efficacy of current cancer therapies has led other areas of science …

Recent advancement of nanomedicine-based targeted delivery for cervical cancer treatment

R Yadav, PP Das, S Sharma, S Sengupta, D Kumar… - Medical Oncology, 2023 - Springer
Cervical cancer is a huge worldwide health burden, impacting women in impoverished
nations in particular. Traditional therapeutic approaches, such as surgery, radiation therapy …

Anthelminthic drug niclosamide sensitizes the responsiveness of cervical cancer cells to paclitaxel via oxidative stress-mediated mTOR inhibition

L Chen, L Wang, H Shen, H Lin, D Li - Biochemical and biophysical …, 2017 - Elsevier
Drug repurposing represents an alternative therapeutic strategy to cancer treatment. The
potent anti-cancer activities of a FDA-approved anthelminthic drug niclosamide have been …