Importance Acute coronary syndrome (ACS) is a major cause of morbidity and mortality in
the United States with an annual incidence of approximately 1 million. Dual antiplatelet …

ANGIOLILLO DJ et al. large-and medium-sized arteries triggers platelet activation, leading to
thrombotic occlusion of the blood vessels. 1 The thrombi block blood flow and oxygen …

CO-CHAIRS: Feldman D: Minneapolis Heart Institute, Minneapolis, Minnesota, Georgia
Institute of Technology and Morehouse School of Medicine; Pamboukian SV: University of …

Aspirin is effective in the prevention of cardiovascular events in high-risk patients. The
primary established effect of aspirin on hemostasis is to impair platelet aggregation via …

OBJECTIVE: Many recommendations for aspirin in stable cardiovascular disease are based
on analyses of all antiplatelet therapies at all dosages and in both stable and unstable …

Aspirin resistance describes a phenomenon where patients receiving aspirin therapy do not
respond favorably to treatment, and is categorized by continued incidence of adverse …

Aspirin is one of the cornerstones of treatment for cardiovascular disease. However, some
patients may be 'resistant'to its effect: this is associated with adverse cardiovascular …

Aspirin-induced cyclooxygenase (COX)-1 acetylation is irreversible and it is assumed that
the platelet thromboxane-A2 aggregation pathway is inhibited for at least 24 hours (h) after …

Rationale: Stent implantation into atherosclerotic plaques releases, apart from particulate
debris, soluble substances that contribute to impaired microvascular perfusion. Objective: To …

BACKGROUND: Diabetes is associated with a high rate of events after acute coronary
syndrome and percutaneous coronary intervention despite aspirin treatment. Once daily …