The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of
contents from the intestinal lumen into the intestinal tissue and systemic circulation. A …

Weaning is considered to be one of the most critical periods in pig production, which is
related to the economic benefits of pig farms. However, in actual production, many piglets …

Bipolar disorders (BD) represent a severe leading disabling mental condition worldwide
characterized by episodic and often progressive mood fluctuations with manic and …

Cancer is a group of cells that malignantly grow and proliferate uncontrollably. At present,
treatment modes for cancer mainly comprise surgery, chemotherapy, radiotherapy …

Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss
(lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a …

Background The intestinal mucosa is composed of a well-organized epithelium, acting as a
physical barrier to harmful luminal contents, while simultaneously ensuring absorption of …

Patients with ulcerative colitis (UC) are at a two-to three-fold increased risk of developing
colorectal cancer (CRC) than the general population based on population-based data. UC …

Background & Aims Defects in the epithelial tight junction (TJ) barrier contribute to
development of intestinal inflammation associated with diseases. Interleukin 1 beta (IL1B) …

Inflammatory lung diseases like asthma bronchiale, chronic obstructive pulmonary disease
and allergic airway inflammation are widespread public diseases that constitute an …

Inflammation caused by either intrinsic or extrinsic toxins results in intestinal barrier
dysfunction, contributing to inflammatory bowel disease (IBD) and other diseases. Vitamin A …