[HTML][HTML] The contribution of extracellular vesicles from senescent endothelial and vascular smooth muscle cells to vascular calcification
Vascular calcification is an irreversible pathological process associated with a loss of
vascular wall function. This process occurs as a result of aging and age-related diseases …
vascular wall function. This process occurs as a result of aging and age-related diseases …
[HTML][HTML] Endoplasmic reticulum stress and pathogenesis of vascular calcification
Z Rao, Y Zheng, L Xu, Z Wang, Y Zhou… - Frontiers in …, 2022 - frontiersin.org
Vascular calcification (VC) is characterized by calcium phosphate deposition in blood vessel
walls and is associated with many diseases, as well as increased cardiovascular morbidity …
walls and is associated with many diseases, as well as increased cardiovascular morbidity …
Annexin A5 derived from matrix vesicles protects against osteoporotic bone loss via mineralization
G Su, D Zhang, T Li, T Pei, J Yang, S Tu, S Liu, J Ren… - Bone Research, 2023 - nature.com
Matrix vesicles (MVs) have shown strong effects in diseases such as vascular ectopic
calcification and pathological calcified osteoarthritis and in wound repair of the skeletal …
calcification and pathological calcified osteoarthritis and in wound repair of the skeletal …
The functional role of soluble proteins acquired by extracellular vesicles
Extracellular vesicles (EVs) are lipid bilayer‐enclosed nanosized particles released by all
cell types during physiological as well as pathophysiological processes to carry out diverse …
cell types during physiological as well as pathophysiological processes to carry out diverse …
Do Media Extracellular Vesicles and Extracellular Vesicles Bound to the Extracellular Matrix Represent Distinct Types of Vesicles?
Mineralization-competent cells, including hypertrophic chondrocytes, mature osteoblasts,
and osteogenic-differentiated smooth muscle cells secrete media extracellular vesicles …
and osteogenic-differentiated smooth muscle cells secrete media extracellular vesicles …
Vascular calcification: from the perspective of crosstalk
S Yang, Z Zeng, Q Yuan, Q Chen, Z Wang, H Xie… - Molecular …, 2023 - Springer
Vascular calcification (VC) is highly correlated with cardiovascular disease morbidity and
mortality, but anti-VC treatment remains an area to be tackled due to the ill-defined …
mortality, but anti-VC treatment remains an area to be tackled due to the ill-defined …
The role and applications of extracellular vesicles in osteoporosis
F Fang, J Yang, J Wang, T Li, E Wang, D Zhang, X Liu… - Bone Research, 2024 - nature.com
Osteoporosis is a widely observed condition characterized by the systemic deterioration of
bone mass and microarchitecture, which increases patient susceptibility to fragile fractures …
bone mass and microarchitecture, which increases patient susceptibility to fragile fractures …
Ectopic mineralization-inspired cell membrane-based matrix vesicle analogs for in-depth remineralization of dentinal tubules for treating dentin hypersensitivity
M Li, X Zheng, Z Dong, Y Zhang, W Wu, X Chen… - Nano Research, 2023 - Springer
The invasion of etched dentinal tubules (DTs) by external substances induces dentin
hypersensitivity (DH). The deep and compact occlusion of DTs is highly desirable for treating …
hypersensitivity (DH). The deep and compact occlusion of DTs is highly desirable for treating …
[HTML][HTML] Interstitial Fluid Shear Stress Induces the Synthetic Phenotype Switching of VSMCs to Release Pro-calcified Extracellular Vesicles via EGFR-MAPK-KLF5 …
W Gao, K Gu, L Ma, F Yang, L Deng… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Phenotypic switching (from contractile to synthetic) of vascular smooth muscle cells (VSMCs)
is essential in the progression of atherosclerosis. The damaged endothelium in the …
is essential in the progression of atherosclerosis. The damaged endothelium in the …
[HTML][HTML] Unraveling the role of carboxylate groups and elastin particle size in medial calcification
T Son, M Cerruti - International Journal of Biological Macromolecules, 2024 - Elsevier
While it is known that calcium phosphate (CaP) minerals deposit in elastin-rich medial layers
of arteries during medial calcification, their nucleation and growth sites are still debated …
of arteries during medial calcification, their nucleation and growth sites are still debated …