The delivery of high quality and equitable care for both mothers and newborns is complex
and requires efforts across many sectors. The United States spends more on childbirth than …

Background Women are commonly prescribed a variety of medications during pregnancy.
As most organ systems are affected by the substantial anatomical and physiological …

Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

Zika virus, influenza, and Ebola have called attention to the ways in which infectious disease
outbreaks can severely–and at times uniquely–affect the health interests of pregnant women …

Objective Pregnant women have been historically excluded from clinical trials for
nonobstetric conditions, even during prior epidemics. The objective of this review is to …

Background Since pregnant women are severely underrepresented in clinical research,
many take the position that the exclusion of pregnant women from research must be justified …

The use of prescribed and over-the-counter medications in pregnancy is on the rise. Many
women become pregnant at an older age and with preexisting medical conditions that …

Objective To undertake a survey of the world's clinical trial registries to provide current data
on the number, nature, funding source and geographical distribution of pregnancy drug trials …

Clinical pharmacology studies that describe the pharmacokinetics and pharmacodynamics
of drugs in pregnant women are critical for informing on the safe and effective use of drugs …

Drugs can have harmful effects on the embryo or the fetus at any point during pregnancy.
Not all the damaging effects of intrauterine exposure to drugs are obvious at birth, some may …