Recent Advances in the Total Synthesis of the Tetrahydroisoquinoline Alkaloids (2002–2020)

AN Kim, A Ngamnithiporn, E Du, BM Stoltz - Chemical Reviews, 2023 - ACS Publications
The tetrahydroisoquinoline (THIQ) natural products constitute one of the largest families of
alkaloids and exhibit a wide range of structural diversity and biological activity. Ranging from …

[HTML][HTML] Natural aporphine alkaloids: A comprehensive review of phytochemistry, pharmacokinetics, anticancer activities, and clinical application

J Sun, X Zhan, W Wang, X Yang, Y Liu, H Yang… - Journal of Advanced …, 2023 - Elsevier
Background Cancer is the most common cause of death and is still a serious public health
problem. Alkaloids, a class of bioactive compounds widely diffused in plants, especially …

[HTML][HTML] Nuciferine Effectively Protects Mice against Acetaminophen-Induced Liver Injury

Z Zhou, J Qi, Y Wu, C Li, W Bao, X Lin, A Zhu - Antioxidants, 2023 - mdpi.com
Acetaminophen (APAP) overdose still poses a major clinical challenge and is a leading
cause of acute liver injury (ALI). N-acetylcysteine (NAC) is the only approved antidote to treat …

Chemistry and biology of nuciferine

X Huang, N Hao, G Chen, S Liu, Z Che - Industrial Crops and Products, 2022 - Elsevier
Nuciferine is an aporphine alkaloid first isolated from Nelumbo nucifera Gaertn as the main
bioactive ingredient. Additionally, it was also obtained from some other plants. Nuciferine …

[HTML][HTML] Alkaloids in future drug discovery

MJU Ferreira - Molecules, 2022 - mdpi.com
Alkaloids are nitrogen-containing compounds, biosynthesized by both marine and terrestrial
organisms, often with strong biological properties. They are among the largest classes of …

Therapeutic potential of alkaloid extract from Codonopsis Radix in alleviating hepatic lipid accumulation: insights into mitochondrial energy metabolism and …

FAN Cailian, W Guan, C Miao, LI Yao, T Xiyang… - Chinese Journal of …, 2023 - Elsevier
Alkaloids are a class of naturally occurring bioactive compounds that are widely distributed
in various food sources and Traditional Chinese Medicine. This study aimed to investigate …

North American pawpaw (Asimina triloba L.) fruit: A critical review of bioactive compounds and their bioactivities.

B Adainoo - Trends in Food Science & Technology, 2024 - Elsevier
Abstract Background The North American pawpaw (Asimina triloba L.) fruit is an
underutilized specialty crop native to North America. Due to the short shelf life of the fruit, it …

[HTML][HTML] A Study of the Chemical Composition and Biological Activity of Michelia macclurei Dandy Heartwood: New Sources of Natural Antioxidants, Enzyme …

S Chen, B Wei, Y Fu - International Journal of Molecular Sciences, 2023 - mdpi.com
The wood of Michelia macclurei Dandy (MD) is an excellent material that is widely used in
the furniture, handicraft, and construction industries. However, less research has been …

Development of a tamarind-based functional beverage with partially-hydrolyzed agave syrup and the health effects of its consumption in C57BL/6 mice

R Cardona-Herrera, TA Quiñones-Muñoz… - Food Chemistry, 2024 - Elsevier
Excess consumption of sweetened beverages is associated with a global rise in metabolic
diseases. Tamarind and partially-hydrolyzed agave syrup have potential for developing …

[HTML][HTML] Advocacy for the Medicinal Plant Artabotrys hexapetalus (Yingzhao) and Antimalarial Yingzhaosu Endoperoxides

C Bailly, JP Hénichart - Molecules, 2022 - mdpi.com
The medicinal plant Artabotrys hexapetalus (synonyms: A. uncinatus and A. odoratissimus)
is known as yingzhao in Chinese. Extracts of the plant have long been used in Asian folk …