Carbohydrate diversity is foundational in the molecular literacy that regulates cellular
function and communication. Consequently, delineating and leveraging this structure …

Short aliphatic groups are prevalent in bioactive small molecules and play an essential role
in regulating physicochemistry and molecular recognition phenomena. Delineating their …

1, 1-Disubstituted styrenes with internal oxygen and nitrogen nucleophiles undergo
oxidative fluorocyclization reactions with in situ generated chiral iodine (III)-catalysts. The …

The introduction of fluorine atoms into molecules and materials across many fields of
academic and industrial research is now commonplace, owing to their unique properties. A …

The prominence and versatility of propargylic fluorides in medicinal chemistry, coupled with
the potency of F/H and F/OH bioisosterism, has created a powerful impetus to develop …

Fluorinated compounds are widely used in the fields of molecular imaging, pharmaceuticals,
and materials. Fluorinated natural products in nature are rare, and the introduction of …

Homologation of trisubstituted fluoroalkenes followed by allylboration of aldehyde, ketone
and imine substrates is suitable for synthesis of β‐fluorohydrin and amine products. In the …

We have quantum chemically investigated the rotational isomerism of 1, 2‐dihaloethanes
XCH2CH2X (X= F, Cl, Br, I) at ZORA‐BP86‐D3 (BJ)/QZ4P. Our Kohn‐Sham molecular …

Fluorine-containing organic molecules, particularly those that bear (sp3) C–F bonds, are
rapidly gaining prominence in modern chemical synthesis. Although extensive studies have …

Single site OH→ F substitution at the termini of maltotetraose leads to significantly improved
hydrolytic stability towards α-amylase and α-glucosidase relative to the natural compound …