Guidelines on models of diabetic heart disease

LC Heather, AD Hafstad, GV Halade… - American Journal …, 2022 - journals.physiology.org
Diabetes is a major risk factor for cardiovascular diseases, including diabetic
cardiomyopathy, atherosclerosis, myocardial infarction, and heart failure. As cardiovascular …

Intracellular to interorgan mitochondrial communication in striated muscle in health and disease

NT Boardman, G Trani, M Scalabrin… - Endocrine …, 2023 - academic.oup.com
Mitochondria sense both biochemical and energetic input in addition to communicating
signals regarding the energetic state of the cell. Increasingly, these signaling organelles are …

[HTML][HTML] Impairment of mitochondrial respiration in metabolic diseases: an overview

VF Avram, AP Merce, IM Hâncu, AD Bătrân… - International Journal of …, 2022 - mdpi.com
Mitochondrial dysfunction has emerged as a central pathomechanism in the setting of
obesity and diabetes mellitus, linking these intertwined pathologies that share insulin …

Bacterial diversity in intestinal mucosa of mice fed with Dendrobium officinale and high-fat diet

X Li, X Peng, K Guo, Z Tan - 3 Biotech, 2021 - Springer
This study aimed to explore the effect of Dendrobium officinale (DO) on the diversity of
intestinal mucosal flora in high-fat diet mice and provided an experimental basis for the …

[HTML][HTML] The link between obesity and aging-insights into cardiac energy metabolism

P Owesny, T Grune - Mechanisms of Ageing and Development, 2023 - Elsevier
Obesity and aging are well-established risk factors for a range of diseases, including
cardiovascular diseases and type 2 diabetes. Given the escalating prevalence of obesity …

[HTML][HTML] Lipotoxicity, mitotoxicity, and drug targets

N Krako Jakovljevic, NT Boardman… - Frontiers in …, 2023 - frontiersin.org
Lipotoxicity is the dysregulation of the lipid environment leading to the accumulation of
harmful lipids that can lead to organelle dysfunction, cellular injury, and cell death. It is often …

Mitochondrial Respiration, Cardiac Function and Hemodynamics in Rats on High-Calorie Diets with Metabolic Syndrome and Diabetes

E Ivanov, M Akhmetshina, A Erdiakov, A Gizatulina… - 2023 - preprints.org
In a 24-week-long experiment, 31 rats were assigned to one of 3groups: a Control group
receiving standard chow and water, a Fructose group receiving standard chow and a 20 …

Lipotoxicity, mitotoxicity, and drug targets.

NT Boardman, M Makrecka-Kuka - Frontiers in Endocrinology, 2023 - europepmc.org
Lipotoxicity is the dysregulation of the lipid environment leading to the accumulation of
harmful lipids that can lead to organelle dysfunction, cellular injury, and cell death. It is often …

High Palmitate Alters Glutathione Redox During Severe Oxidant Stress in the Heart; An Evaluation of Altered Glutathione Redox Environment on Cardiac Function and …

R Sepehrara - 2021 - munin.uit.no
When the heart is under stress, eg ischemia-reperfusion (IR), it produces an enormous
amount of reactive oxygen species (ROS). Glutathione, which is an endogenous antioxidant …