Nutrition, physical activity, and other lifestyle factors in the prevention of cognitive decline and dementia

LJ Dominguez, N Veronese, L Vernuccio, G Catanese… - Nutrients, 2021 - mdpi.com
Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

[HTML][HTML] Insular cortex neurons encode and retrieve specific immune responses

T Koren, M Amer, M Krot, N Boshnak, TL Ben-Shaanan… - Cell, 2021 - cell.com
Increasing evidence indicates that the brain regulates peripheral immunity, yet whether and
how the brain represents the state of the immune system remains unclear. Here, we show …

[HTML][HTML] Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells

QY Ang, M Alexander, JC Newman, Y Tian, J Cai… - Cell, 2020 - cell.com
Very low-carbohydrate, high-fat ketogenic diets (KDs) induce a pronounced shift in
metabolic fuel utilization that elevates circulating ketone bodies; however, the …

Contribution of the intestinal microbiome and gut barrier to hepatic disorders

DM Chopyk, A Grakoui - Gastroenterology, 2020 - Elsevier
Intestinal barrier dysfunction and dysbiosis contribute to development of diseases in liver
and other organs. Physical, immunologic, and microbiologic (bacterial, fungal, archaeal …

Organoids in immunological research

YE Bar-Ephraim, K Kretzschmar… - Nature Reviews …, 2020 - nature.com
Much of our knowledge regarding the interactions between epithelial tissues and the
immune system has been gathered from animal models and co-cultures with cell lines …

Unhealthy lifestyle and gut dysbiosis: a better understanding of the effects of poor diet and nicotine on the intestinal microbiome

JE Martinez, DD Kahana, S Ghuman… - Frontiers in …, 2021 - frontiersin.org
The study of the intestinal or gut microbiome is a newer field that is rapidly gaining attention.
Bidirectional communication between gut microbes and the host can impact numerous …

Understanding the physiology of human defaecation and disorders of continence and evacuation

PT Heitmann, PF Vollebregt, CH Knowles… - Nature reviews …, 2021 - nature.com
The act of defaecation, although a ubiquitous human experience, requires the coordinated
actions of the anorectum and colon, pelvic floor musculature, and the enteric, peripheral and …

Fecal microbiota transplantation relieves gastrointestinal and autism symptoms by improving the gut microbiota in an open-label study

N Li, H Chen, Y Cheng, F Xu, G Ruan… - Frontiers in cellular …, 2021 - frontiersin.org
Autism spectrum disorder (ASD) is a severe brain development disorder that is
characterized by deficits in social communication and restricted, repetitive and stereotyped …

High-coverage metabolomics uncovers microbiota-driven biochemical landscape of interorgan transport and gut-brain communication in mice

Y Lai, CW Liu, Y Yang, YC Hsiao, H Ru, K Lu - Nature communications, 2021 - nature.com
The mammalian gut harbors a complex and dynamic microbial ecosystem: the microbiota.
While emerging studies support that microbiota regulates brain function with a few molecular …