Immune and inflammatory mechanisms in hypertension

TJ Guzik, R Nosalski, P Maffia… - Nature Reviews …, 2024 - nature.com
Hypertension is a global health problem, with> 1.3 billion individuals with high blood
pressure worldwide. In this Review, we present an inflammatory paradigm for hypertension …

[HTML][HTML] Microcirculation in hypertension: a therapeutic target to prevent cardiovascular disease?

D Rizzoni, C Agabiti-Rosei, GEM Boari… - Journal of Clinical …, 2023 - mdpi.com
Arterial hypertension is a common condition worldwide and an important risk factor for
cardio-and cerebrovascular events, renal diseases, as well as microvascular eye diseases …

[HTML][HTML] Three-dimensional identification of microvascular pathology and neurovascular inflammation in severe white matter hyperintensity: a case report

G Solé-Guardia, M Luijten, B Geenen… - Scientific Reports, 2024 - nature.com
White matter hyperintensities (WMH) are the most prevalent markers of cerebral small vessel
disease (SVD), which is the major vascular risk factor for dementia. Microvascular pathology …

Prognostic significance of the wall to lumen ratio of retinal arterioles evaluated by adaptive optics

C De Ciuceis, CA Rosei, P Malerba, C Rossini… - European Journal of …, 2024 - Elsevier
Objective Microvascular structural alterations may be considered an important form of
hypertension-mediated organ damage. An increased media-to-lumen ratio of subcutaneous …

[HTML][HTML] Endothelial Senescence: From Macro-to Micro-Vasculature and Its Implications on Cardiovascular Health

P Wang, D Konja, S Singh, B Zhang… - International Journal of …, 2024 - mdpi.com
Endothelial cells line at the most inner layer of blood vessels. They act to control hemostasis,
arterial tone/reactivity, wound healing, tissue oxygen, and nutrient supply. With age …

[HTML][HTML] Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and …

R Rodrigues-Diez, C Ballesteros-Martinez… - Biomedicine & …, 2024 - Elsevier
During resolution of inflammation, specialized proresolving mediators (SPMs), including
resolvins, are produced to restore tissue homeostasis. We hypothesized that there might be …

[HTML][HTML] Microvascular rarefaction caused by the NOTCH signaling pathway is a key cause of TKI-apatinib-induced hypertension and cardiac damage

WJ Wang, G Li, J Ma, X Fan, J Lu, Q Sun… - Frontiers in …, 2024 - frontiersin.org
With the advancement of tumour-targeted therapy technology, the survival of cancer patients
has continued to increase, and cardiovascular events have gradually become an important …

The Impact of Disease Duration on Microcirculatory Dysfunction in Young Patients with Uncomplicated Type 1 Diabetes

J Neubauer-Geryk, M Wielicka, M Hoffmann… - Biomedicines, 2024 - mdpi.com
This study aimed to evaluate the earliest changes in the structure and function of the
peripheral microcirculation using capillaroscopy and transcutaneous oxygen pressure …

Thirty-five years of the European Society of Hypertension: from past to future

G Grassi - Journal of Hypertension, 2024 - journals.lww.com
Abstract The European Society of Hypertension (ESH) was established 35 years ago. Since
then, it promoted and coordinated a number of activities which include educational projects …