Comprehensive review of targeted therapy for colorectal cancer
YH Xie, YX Chen, JY Fang - Signal transduction and targeted therapy, 2020 - nature.com
Colorectal cancer (CRC) is among the most lethal and prevalent malignancies in the world
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …
and was responsible for nearly 881,000 cancer-related deaths in 2018. Surgery and …
The role of microenvironment in tumor angiogenesis
X Jiang, J Wang, X Deng, F Xiong, S Zhang… - Journal of Experimental …, 2020 - Springer
Tumor angiogenesis is necessary for the continued survival and development of tumor cells,
and plays an important role in their growth, invasion, and metastasis. The tumor …
and plays an important role in their growth, invasion, and metastasis. The tumor …
[HTML][HTML] The impact of VEGF on cancer metastasis and systemic disease
Metastasis is the leading cause of cancer-associated mortality and the underlying
mechanisms of cancer metastasis remain elusive. Both blood and lymphatic vasculatures …
mechanisms of cancer metastasis remain elusive. Both blood and lymphatic vasculatures …
The anti-cancer effect of quercetin: molecular implications in cancer metabolism
M Reyes-Farias, C Carrasco-Pozo - International journal of molecular …, 2019 - mdpi.com
Cancer is a problem with worldwide importance and is the second leading cause of death
globally. Cancer cells reprogram their metabolism to support their uncontrolled expansion …
globally. Cancer cells reprogram their metabolism to support their uncontrolled expansion …
[PDF][PDF] Vascular endothelial growth factor (VEGF)-key factor in normal and pathological angiogenesis
Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …
[HTML][HTML] Contribution of angiogenesis to inflammation and cancer
D Aguilar-Cazares, R Chavez-Dominguez… - Frontiers in …, 2019 - frontiersin.org
During carcinogenesis, advanced tumors are surrounded by both stromal and immune cells,
which support tumor development. In addition, inflammation and angiogenesis are …
which support tumor development. In addition, inflammation and angiogenesis are …
[HTML][HTML] Mechanisms of blue light-induced eye hazard and protective measures: a review
X Ouyang, J Yang, Z Hong, Y Wu, Y Xie… - Biomedicine & …, 2020 - Elsevier
The risk of blue light exposure to human health has attracted increased research attention.
Blue light, with relatively high energy, can cause irreversible photochemical damage to eye …
Blue light, with relatively high energy, can cause irreversible photochemical damage to eye …
[HTML][HTML] The role of the VEGF family in coronary heart disease
Y Zhou, X Zhu, H Cui, J Shi, G Yuan, S Shi… - Frontiers in …, 2021 - frontiersin.org
The vascular endothelial growth factor (VEGF) family, the regulator of blood and lymphatic
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …
vessels, is mostly investigated in the tumor and ophthalmic field. However, the functions it …
Monocytes deposit migrasomes to promote embryonic angiogenesis
C Zhang, T Li, S Yin, M Gao, H He, Y Li, D Jiang… - Nature Cell …, 2022 - nature.com
Pro-angiogenic factors are key regulators of angiogenesis. Here we report that highly
migratory cells patrol the area of capillary formation in chick embryo chorioallantoic …
migratory cells patrol the area of capillary formation in chick embryo chorioallantoic …
[HTML][HTML] Lenvatinib for hepatocellular carcinoma: From preclinical mechanisms to anti-cancer therapy
Y Zhao, YN Zhang, KT Wang, L Chen - Biochimica et Biophysica Acta (BBA …, 2020 - Elsevier
Lenvatinib, a multi-target tyrosine kinase inhibitor (TKI), is an emerging first-line therapy for
hepatocellular carcinoma (HCC). Its application has changed the status of sorafenib as the …
hepatocellular carcinoma (HCC). Its application has changed the status of sorafenib as the …