[HTML][HTML] Targeting TRP channels for pain relief: A review of current evidence from bench to bedside
Several decades of research support the involvement of transient receptor potential (TRP)
channels in nociception. Despite the disappointments of early TRPV1 antagonist programs …
channels in nociception. Despite the disappointments of early TRPV1 antagonist programs …
[HTML][HTML] Pathogenic mechanisms and therapeutic approaches in obesity-related knee osteoarthritis
R Shumnalieva, G Kotov, P Ermencheva, S Monov - Biomedicines, 2023 - mdpi.com
The knee is the joint most frequently involved in osteoarthritis, a common joint disorder in the
adult population that is associated with significant chronic joint pain, reduced mobility and …
adult population that is associated with significant chronic joint pain, reduced mobility and …
Mechanisms of oxidative stress in interstitial cystitis/bladder pain syndrome
A Mohammad, MA Laboulaye, C Shenhar… - Nature Reviews …, 2024 - nature.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by bladder and/or pelvic
pain, increased urinary urgency and frequency and nocturia. The pathophysiology of IC/BPS …
pain, increased urinary urgency and frequency and nocturia. The pathophysiology of IC/BPS …
Promising therapeutic targets for the treatment of urine storage dysfunction: what's the status?
KE Andersson - Expert Opinion on Therapeutic Targets, 2024 - Taylor & Francis
Introduction Opinions differ on what drugs have both a rationale and a development
potential for the treatment of bladder storage dysfunction. Areas covered In the present …
potential for the treatment of bladder storage dysfunction. Areas covered In the present …
[HTML][HTML] Transcriptome Analysis of Rheumatoid Arthritis Uncovers Genes Linked to Inflammation-Induced Pain
BE Hall, K Mazhar, E Macdonald, M Cassidy… - Research …, 2024 - ncbi.nlm.nih.gov
Autoimmune diseases such as rheumatoid arthritis (RA) can promote states of chronic
Inflammation with accompanying tissue destruction and pain. RA can cause inflammatory …
Inflammation with accompanying tissue destruction and pain. RA can cause inflammatory …
[HTML][HTML] History of TRP channels and lower urinary tract function and dysfunction
KE Andersson - Continence, 2024 - Elsevier
The history of TRP channels and bladder started in the 1980-ies with the studies of Maggi
and collaborators, who created the basis for using capsaicin and other vanilloids in LUT …
and collaborators, who created the basis for using capsaicin and other vanilloids in LUT …
[引用][C] Anti-cancer activity of capsaicin and its analogs in gynecological cancers
KC Brown, AM Sugrue, KB Conley, KJ Modi, RS Light… - 2024 - Elsevier