With an increasing number of patients with cystic fibrosis (CF) receiving highly effective
CFTR (cystic fibrosis transmembrane regulator protein) modulator therapy, particularly at a …

Magnetic resonance imaging (MRI) plays a significant role in the routine imaging workflow,
providing both anatomical and functional information. 19F MRI is an evolving imaging …

Background Regional flow volume loop ventilation‐weighted noncontrast‐enhanced proton
lung MRI in free breathing has emerged as a novel technique for assessment of regional …

Background Non‐contrast‐enhanced 1H magnetic resonance imaging (MRI) with full lung
coverage shows promise for assessment of regional lung ventilation but a comparison with …

Multi-modality (or multi-channel) imaging is becoming increasingly important and more
widely available, eg hyperspectral imaging in remote sensing, spectral CT in material …

The recent introduction of triple-combination CF transmembrane regulator therapy has put
further emphasis on the need for sensitive methods of monitoring treatment response to …

Purpose To quantitatively compare dynamic 19F and single breath hyperpolarized 129Xe
MRI for the detection of ventilation abnormalities in subjects with mild cystic fibrosis (CF) …

Sodium (23Na) yields the second strongest nuclear magnetic resonance (NMR) signal in
biological tissues and plays a vital role in cell physiology. Sodium magnetic resonance …

Purpose Dynamic nuclear polarization is an emerging imaging method that allows
noninvasive investigation of tissue metabolism. However, the relatively low metabolic spatial …

Purpose To examine the time‐dependent diffusion of fluorinated (19F) gas in human lungs
for determination of surface‐to‐volume ratio in comparison to results from hyperpolarized …