Tryptophan is an essential amino acid, going through three different metabolic pathways in
the intestines. Indole pathway in the gut microbiota, serotonin system in the enterochromaffin …

Simple Summary Tricyclic antidepressants (TCAs) are old and known therapeutic agents
whose good safety profile makes them good candidates for drug repurposing. As the …

Symptoms of depression are present in over half of all cancer patients, and selective
serotonin reuptake inhibitor (SSRI) anti‑depressant medications are prescribed to nearly a …

Both depressive and malignant disorders are endemic, furthermore, they are also frequently
comorbid. In this narrative review, we briefly discuss the epidemiological aspects of the …

To provide systematic insight into the composition and expression of transfer RNA (tRNA)
derivatives transcriptome in colorectal cancer (CRC). tRNA derivatives expression profiles in …

Simple Summary Individuals with a family history of colorectal cancer (CRC) are at a high
risk of developing CRC. We performed a nationwide cohort study to explore whether …

Background Colorectal cancer (CRC) is regarded as a multifactorial disease and shares
many risk factors with alcoholism. However, the association between alcoholism and CRC …

Background The co‐occurrence of depression and diabetes mellitus has been linked to an
increased risk of developing cancer. This study aimed to investigate whether depression …

Aim The aim of this paper is to clarify the inconsistent findings in the association between
antidepressant use and the risk of epithelial ovarian cancer (EOC). Methods This study is a …

Background Preclinical studies have suggested that antidepressant drugs may possess
antineoplastic properties. In a nationwide case–control study, we examined the association …