Since reports published in 2015 and 2016 identified 15 probable exposure–outcome
associations, there has been an increase in studies in humans of exposure to endocrine …

Global plastics production has reached 380 million metric tons in 2015, with around 40%
used for packaging. Plastic packaging is diverse and made of multiple polymers and …

Reliable synthesis of the various rapidly expanding bodies of evidence is vital for the
process of evidence-informed decision-making in environmental policy, practice and …

Endocrine-disrupting chemicals (EDCs) substantially cost society as a result of increases in
disease and disability but—unlike other toxicant classes such as carcinogens—have yet to …

Advances in the biological sciences have led to an ongoing paradigm shift in toxicity testing
based on expanded application of high-throughput in vitro screening and in silico methods …

Background Antimicrobial use in food-producing animals selects for antimicrobial resistance
that can be transmitted to humans via food or other transmission routes. The World Health …

The circumstances under which different ecosystem service benefits can be realized differ.
The benefits tend to be coproduced and to be enabled by multiple interacting social …

Background Systematic reviews, which assess the risk of bias in included studies, are
increasingly used to develop environmental hazard assessments and public health …

Humans and wildlife are exposed to an intractably large number of different combinations of
chemicals via food, water, air, consumer products, and other media and sources. This raises …

The Monographs produced by the International Agency for Research on Cancer (IARC)
apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards …