Abstract Pannexin 1 (Panx1) is involved in endothelium-dependent vasodilation in large
arteries, but the exact mechanistic role remains poorly understood. We hypothesized that …

Objective—Pseudoxanthoma elasticum is an inherited metabolic disorder resulting from
ABCC6 gene mutations. It is characterized by progressive calcification and fragmentation of …

Purinergic signaling has been recognized as playing an important role in inflammation,
angiogenesis, malignancy, diabetes and neural transmission. Activation of signaling …

Adenosine is a ubiquitous, endogenous purine involved in a variety of physiological and
pathophysiological regulatory mechanisms. Adenosine has been proposed as an …

Key points We investigated the excitation–contraction coupling mechanisms in small
pulmonary veins (SPVs) in rat precision‐cut lung slices. We found that SPVs contract …

The study of the mechanisms of regulation of vascular tone is an urgent task of modern
science, since diseases of the cardiovascular system remain the main cause of reduction in …

Aims To determine the role played by adenosine, ATP and chemoreflex activation on the
regulation of vascular conductance in chronic hypoxia. Methods The vascular conductance …

Aims Prostate cancer is the second most frequently malignancy in men worldwide. Most
deaths are caused by metastasis, and tumor cell dissemination involves the interaction with …

Association of Migraine and Sleep-Related Breathing Disorder... : Medicine Association of
Migraine and Sleep-Related Breathing Disorder: A Population-Based Cohort Study : Medicine …

Extracellular purines, principally adenosine triphosphate and adenosine, are among the
oldest evolutionary and widespread chemical messengers. The integrative view of …