Neuroprotective effects of quercetin on memory and anxiogenic-like behavior in diabetic rats: Role of ectonucleotidases and acetylcholinesterase activities
The present study investigated the protective effect of quercetin (Querc) on memory, anxiety-
like behavior and impairment of ectonucleotidases and acetylcholinesterase (AChE) …
like behavior and impairment of ectonucleotidases and acetylcholinesterase (AChE) …
Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone
G Kauffenstein, S Tamareille, F Prunier… - … , and vascular biology, 2016 - Am Heart Assoc
Objective—Myogenic tone (MT) of resistance arteries ensures autoregulation of blood flow
in organs and relies on the intrinsic property of smooth muscle to contract in response to …
in organs and relies on the intrinsic property of smooth muscle to contract in response to …
Purinergic signalling during development and ageing
G Burnstock, N Dale - Purinergic signalling, 2015 - Springer
Extracellular purines and pyrimidines play major roles during embryogenesis,
organogenesis, postnatal development and ageing in vertebrates, including humans …
organogenesis, postnatal development and ageing in vertebrates, including humans …
The role of P2Y receptors in regulating immunity and metabolism
Abstract P2Y receptors are G protein-coupled receptors whose physiological agonists are
the nucleotides ATP, ADP, UTP, UDP and UDP-glucose. Eight P2Y receptors have been …
the nucleotides ATP, ADP, UTP, UDP and UDP-glucose. Eight P2Y receptors have been …
P2X receptors and inflammation
F Di Virgilio - Current medicinal chemistry, 2015 - ingentaconnect.com
Until recently, P2X receptors have not received much attention in the context of immunology
and inflammation. While this is justified to a certain extent for P2X1, P2X2, P2X3, P2X5 and …
and inflammation. While this is justified to a certain extent for P2X1, P2X2, P2X3, P2X5 and …
Exercise training modulates functional sympatholysis and α‐adrenergic vasoconstrictor responsiveness in hypertensive and normotensive individuals
SP Mortensen, M Nyberg, L Gliemann… - The Journal of …, 2014 - Wiley Online Library
Key points Essential hypertension is linked to an increased sympathetic vasoconstrictor
activity and reduced tissue perfusion. Exercise training can improve the ability to override …
activity and reduced tissue perfusion. Exercise training can improve the ability to override …
Structural insights into divalent cation modulations of ATP-gated P2X receptor channels
P2X receptors are trimeric ATP-gated cation channels involved in physiological processes
ranging widely from neurotransmission to pain and taste signal transduction. The …
ranging widely from neurotransmission to pain and taste signal transduction. The …
Adenosine metabolism in the vascular system
GG Yegutkin - Biochemical Pharmacology, 2021 - Elsevier
The concept of extracellular purinergic signaling was first proposed by Geoffrey Burnstock in
the early 1970s. Since then, extracellular ATP and its metabolites ADP and adenosine have …
the early 1970s. Since then, extracellular ATP and its metabolites ADP and adenosine have …
Extracellular vesicle-mediated purinergic signaling contributes to host microenvironment plasticity and metastasis in triple negative breast cancer
S Duan, S Nordmeier, AE Byrnes… - International Journal of …, 2021 - mdpi.com
Metastasis accounts for over 90% of cancer-related deaths, yet the mechanisms guiding this
process remain unclear. Secreted nucleoside diphosphate kinase A and B (NDPK) support …
process remain unclear. Secreted nucleoside diphosphate kinase A and B (NDPK) support …
P2Y purinergic receptors, endothelial dysfunction, and cardiovascular diseases
Purinergic G-protein-coupled receptors are ancient and the most abundant group of G-
protein-coupled receptors (GPCRs). The wide distribution of purinergic receptors in the …
protein-coupled receptors (GPCRs). The wide distribution of purinergic receptors in the …