Doxorubicin (DOX) is one of the widely used anti-tumor drugs. However, DOX-induced
cardiotoxicity (DIC) and hepatotoxicity (DIH) are among the side effects that limited its …

In this paper we review the mechanisms of the antitumor effects of Hypericum perforatum
L.(St. John's wort, SJW) and its main active component hyperforin (HPF). SJW extract is …

Polyphenols are naturally occurring compounds found in abundance in fruits and
vegetables. Their health-promoting properties and their use in the prevention and treatment …

Simple Summary Caryophyllane sesquiterpenes are unique natural compounds widely
occurring in nature, especially in plant essential oils, that are characterized by multiple …

Reactive oxygen species (ROS) are metabolic byproducts that regulate various cellular
processes. However, at high levels, ROS induce oxidative stress, which in turn can trigger …

Cancer is one of the leading causes of mortality worldwide. Currently available anticancer
therapeutic strategies are not able to improve the survival rate of patients over the past few …

Cancer remains the leading cause of death and rapidly evolving disease worldwide. The
understanding of disease pathophysiology has improved through advanced research …

Background: Today, cancer is the leading cause of death. It appears that using large
amounts of natural resources reduces the damaging consequences of cancer therapy. Over …

Since the number of drugs based on natural products (NPs) represents a large source of
novel pharmacological entities, NPs have acquired significance in drug discovery. Peru is …

Simple Summary Colorectal cancer (CRC) is a significant cause of death worldwide. The
inefficacy of the current treatment regimens is reflected in the frequent recurrence and …