[HTML][HTML] Natural products as modulators of Nrf2 signaling pathway in neuroprotection

I Moratilla-Rivera, M Sánchez… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases (NDs) affect the West due to the increase in life expectancy.
Nervous cells accumulate oxidative damage, which is one of the factors that triggers and …

Dietary (Poly) phenols and Cognitive Decline: A Systematic Review and Meta‐Analysis of Observational Studies

J Godos, A Micek, P Mena, D Del Rio… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope This study aims to systematically review observational studies investigating the
relation between dietary (poly) phenol consumption and various cognitive outcomes …

[HTML][HTML] Zebrafish: a model deciphering the impact of flavonoids on neurodegenerative disorders

K Mhalhel, M Sicari, L Pansera, J Chen, M Levanti… - Cells, 2023 - mdpi.com
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …

Nature as a source and inspiration for human monoamine oxidase B (hMAO-B) inhibition: A review of the recent advances in chemical modification of natural …

F Melfi, S Carradori, A Angeli… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Over the past 5 years, we have witnessed intense research activity about the
biological potential of natural products (NPs) as human monoamine oxidase B (hMAO-B) …

[HTML][HTML] By-Product Extracts from Castanea sativa Counteract Hallmarks of Neuroinflammation in a Microglial Model

P Marrazzo, M Mandrone, I Chiocchio, L Zambonin… - Antioxidants, 2023 - mdpi.com
Castanea sativa is very common in Italy, and the large amount of waste material generated
during chestnut processing has a high environmental impact. Several studies demonstrated …

[HTML][HTML] Rosmarinic acid alleviate CORT-induced depressive-like behavior by promoting neurogenesis and regulating BDNF/TrkB/PI3K signaling axis

J Zeng, Z Xie, L Chen, X Peng, F Luan, J Hu… - Biomedicine & …, 2024 - Elsevier
Rosmarinic acid (RA), a natural phenolic acid compound with a variety of bioactive
properties. However, the antidepressant activity and mechanism of RA remain unclear. The …

[HTML][HTML] Enhancing Therapeutic Efficacy of Donepezil, an Alzheimer's Disease Drug, by Diplazium esculentum (Retz.) Sw. and Its Phytochemicals

W Inthachat, B Chantong, P Pitchakarn, C Takoon… - Pharmaceuticals, 2024 - mdpi.com
Alzheimer's disease (AD) is the most common type of dementia and a significant concern to
global public health due to the prevalence of aging populations. Donepezil is one of only a …

Development of novel carbon‐based biomedical platforms for intervention in xenotoxicant‐induced Parkinson's disease onset

J Kumar, A Varela‐Ramirez, M Narayan - BMEMat, 2024 - Wiley Online Library
Chronic exposure to herbicides, weedicides, and pesticides is associated with the onset and
progress of neurodegenerative disorders such as Parkinson's disease (PD), Alzheimer's …

[HTML][HTML] In vitro study of the blood–brain barrier transport of natural compounds recovered from agrifood by-products and microalgae

JD Sánchez-Martínez, AR Garcia… - International Journal of …, 2022 - mdpi.com
Agrifood by-products and microalgae represent a low-cost and valuable source of bioactive
compounds with neuroprotective properties. However, the neuroprotective effectiveness of …

[HTML][HTML] A Review of the Popular Uses, Anatomical, Chemical, and Biological Aspects of Kalanchoe (Crassulaceae): A Genus of Plants Known as “Miracle Leaf”

E Assis de Andrade, I Machinski, AC Terso Ventura… - Molecules, 2023 - mdpi.com
Species of the genus Kalanchoe have a long history of therapeutic use in ethnomedicine
linked to their remarkable healing properties. Several species have chemical and …