Inflammation and oxidative stress are elevated in the brain, blood, and adrenal glands during the progression of post-traumatic stress disorder in a predator exposure …

CB Wilson, LD McLaughlin, A Nair, PJ Ebenezer… - PloS one, 2013 - journals.plos.org
This study sought to analyze specific pathophysiological mechanisms involved in the
progression of post-traumatic stress disorder (PTSD) by utilizing an animal model. To …

Symptom severity impacts sympathetic dysregulation and inflammation in post-traumatic stress disorder (PTSD)

IT Fonkoue, PJ Marvar, S Norrholm, Y Li… - Brain, behavior, and …, 2020 - Elsevier
Post-traumatic stress disorder (PTSD) is associated with a greater risk of incident
hypertension and cardiovascular disease. Inflammation, impaired baroreflex sensitivity …

[PDF][PDF] Hypothalamic-pituitary-adrenocortical axis: neuropsychiatric aspects

L Jacobson - Compr Physiol, 2014 - scholar.archive.org
Evidence of aberrant hypothalamic-pituitary-adrenocortical (HPA) activity in many
psychiatric disorders, although not universal, has sparked long-standing interest in HPA …

Physical health burden of PTSD, depression, and their comorbidity in the US veteran population: Morbidity, functioning, and disability

B Nichter, S Norman, M Haller, RH Pietrzak - Journal of psychosomatic …, 2019 - Elsevier
Objective Although it is well-established that posttraumatic stress disorder (PTSD) and major
depressive disorder (MDD) are associated with physical health difficulties among US …

Preeclampsia, gestational diabetes and later risk of cardiovascular disease: Women's experiences and motivation for lifestyle changes explored in focus group …

HL Sandsæter, J Horn, JW Rich-Edwards… - BMC pregnancy and …, 2019 - Springer
Background Preeclampsia (PE) and gestational diabetes mellitus (GDM) are both
associated with increased risk of future cardiovascular disease (CVD). Knowledge of the …

Involvement of the brain–heart axis in the link between PTSD and cardiovascular disease

AV Seligowski, TK Webber, PJ Marvar… - Depression and …, 2022 - Wiley Online Library
Posttraumatic stress disorder (PTSD) has long been associated with a heightened risk of
cardiovascular disease (CVD). A number of mechanisms have been implicated to underlie …

Autonomic and inflammatory consequences of posttraumatic stress disorder and the link to cardiovascular disease

C Brudey, J Park, J Wiaderkiewicz… - American Journal …, 2015 - journals.physiology.org
Stress-and anxiety-related disorders are on the rise in both military and general populations.
Over the next decade, it is predicted that treatment of these conditions, in particular …

Augmentation of extinction and inhibitory learning in anxiety and trauma-related disorders

LAM Lebois, AV Seligowski, JD Wolff… - Annual review of …, 2019 - annualreviews.org
Although the fear response is an adaptive response to threatening situations, a number of
psychiatric disorders feature prominent fear-related symptoms caused, in part, by failures of …

Predator exposure/psychosocial stress animal model of post-traumatic stress disorder modulates neurotransmitters in the rat hippocampus and prefrontal cortex

CB Wilson, PJ Ebenezer, LD McLaughlin, J Francis - PloS one, 2014 - journals.plos.org
Post-Traumatic Stress Disorder (PTSD) can develop in response to a traumatic event
involving a threat to life. To date, no diagnostic biomarkers have been identified for PTSD …

The integrative role of the sigh in psychology, physiology, pathology, and neurobiology

JM Ramirez - Progress in brain research, 2014 - Elsevier
Abstract “Sighs, tears, grief, distress” expresses Johann Sebastian Bach in a musical
example for the relationship between sighs and deep emotions. This review explores the …