The airway epithelium in asthma
BN Lambrecht, H Hammad - Nature medicine, 2012 - nature.com
Asthma is a T lymphocyte–controlled disease of the airway wall caused by inflammation,
overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity …
overproduction of mucus and airway wall remodeling leading to bronchial hyperreactivity …
The airway epithelium: soldier in the fight against respiratory viruses
M Vareille, E Kieninger, MR Edwards… - Clinical microbiology …, 2011 - Am Soc Microbiol
The airway epithelium acts as a frontline defense against respiratory viruses, not only as a
physical barrier and through the mucociliary apparatus but also through its immunological …
physical barrier and through the mucociliary apparatus but also through its immunological …
Lung megakaryocytes are immune modulatory cells
DN Pariser, ZT Hilt, SK Ture… - The Journal of …, 2021 - Am Soc Clin Investig
Although platelets are the cellular mediators of thrombosis, they are also immune cells.
Platelets interact both directly and indirectly with immune cells, impacting their activation and …
Platelets interact both directly and indirectly with immune cells, impacting their activation and …
The sentinel role of the airway epithelium in asthma pathogenesis
ST Holgate - Immunological reviews, 2011 - Wiley Online Library
The adoption of the concept that asthma is primarily a disease most frequently associated
with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the widely held concept …
with elaboration of T‐helper 2 (Th2)‐type inflammation has led to the widely held concept …
[PDF][PDF] Biology of lung dendritic cells at the origin of asthma
BN Lambrecht, H Hammad - Immunity, 2009 - cell.com
Dendritic cells (DCs) initiate and maintain adaptive T helper 2 (Th2) cell responses to
inhaled allergens in asthma. Various functions like antigen uptake, migration to the draining …
inhaled allergens in asthma. Various functions like antigen uptake, migration to the draining …
Toward primary prevention of asthma. Reviewing the evidence for early-life respiratory viral infections as modifiable risk factors to prevent childhood asthma
AS Feldman, Y He, ML Moore… - American journal of …, 2015 - atsjournals.org
A first step in primary disease prevention is identifying common, modifiable risk factors that
contribute to a significant proportion of disease development. Infant respiratory viral infection …
contribute to a significant proportion of disease development. Infant respiratory viral infection …
The role of the airway epithelium and its interaction with environmental factors in asthma pathogenesis
Asthma is an inflammatory disorder of the airways dominated by a Th2-type pattern.
Because of this, most research has focused on investigating the role of allergic pathways …
Because of this, most research has focused on investigating the role of allergic pathways …
Alternatively activated macrophages and impaired phagocytosis of S. aureus in chronic rhinosinusitis
O Krysko, G Holtappels, N Zhang, M Kubica… - Allergy, 2011 - Wiley Online Library
To cite this article: Krysko O, Holtappels G, Zhang N, Kubica M, Deswarte K, Derycke L,
Claeys S, Hammad H, Brusselle GG, Vandenabeele P, Krysko DV, Bachert C. Alternatively …
Claeys S, Hammad H, Brusselle GG, Vandenabeele P, Krysko DV, Bachert C. Alternatively …
Non-redundant functions of IL-6 produced by macrophages and dendritic cells in allergic airway inflammation
EO Gubernatorova, EA Gorshkova… - Frontiers in …, 2018 - frontiersin.org
Asthma is a common inflammatory disease of the airway caused by a combination of genetic
and environmental factors and characterized by airflow obstruction, wheezing, eosinophilia …
and environmental factors and characterized by airflow obstruction, wheezing, eosinophilia …
Effects of mesenchymal stem cells from human induced pluripotent stem cells on differentiation, maturation, and function of dendritic cells
Abstract Background Mesenchymal stem cells (MSCs) have potent immunomodulatory
effects on multiple immune cells and have great potential in treating immune disorders …
effects on multiple immune cells and have great potential in treating immune disorders …