[HTML][HTML] A systematic review and meta-analysis of genotype-based and individualized data analysis of SLCO1B1 gene and statin-induced myopathy

S Turongkaravee, J Jittikoon, T Lukkunaprasit… - The …, 2021 - nature.com
This meta-analysis was conducted to determine the genotypic effects of rs4149056 and
rs2306283 polymorphism in SLCO1B1 gene on myopathy in patients with statin. Studies …

[HTML][HTML] Association between SLCO1B1 gene T521C polymorphism and statin-related myopathy risk: a meta-analysis of case–control studies

Q Hou, S Li, L Li, Y Li, X Sun, H Tian - Medicine, 2015 - journals.lww.com
Statin-related myopathy is an important adverse effect of statin which is classically
unpredictable. The evidence of association between solute carrier organic anion transporter …

[HTML][HTML] The SNPs rs429358 and rs7412 of APOE gene are association with cerebral infarction but not SNPs rs2306283 and rs4149056 of SLCO1B1 gene in …

H Wu, Q Huang, Z Yu, H Wu, Z Zhong - Lipids in Health and Disease, 2020 - Springer
Abstract Background Apolipoprotein E (ApoE) and solute carrier organic anion transporter
family member 1B1 (SLCO1B1) regulate lipid metabolism. However, the relationship …

APOE gene ɛ4 allele (388C‐526C) effects on serum lipids and risk of coronary artery disease in southern Chinese Hakka population

Q Liu, H Wu, Z Yu, Q Huang… - Journal of Clinical …, 2021 - Wiley Online Library
Objective To analyze the relationship of Apolipoprotein E (APOE) and solute carrier organic
anion transporter family member 1B1 (SLCO1B1) gene polymorphisms with coronary artery …

[HTML][HTML] Marked differences in frequencies of statin therapy relevant SLCO1B1 variants and haplotypes between Roma and Hungarian populations

A Nagy, C Sipeky, R Szalai, BI Melegh, P Matyas… - BMC genetics, 2015 - Springer
Background SLCO1B1 polymorphisms are relevant in statin pharmacokinetics. Aim of this
study was to investigate the genetic variability and haplotype profile of SLCO1B1 …

Lack of association between SLCO1B1 polymorphisms and lipid‐lowering response to simvastatin therapy in Thai hypercholesterolaemic patients

N Kaewboonlert, W Thitisopee… - Journal of Clinical …, 2018 - Wiley Online Library
What is known SLCO 1B1 polymorphisms have been reported to affect the responses to
statin therapy. However, the association of these polymorphisms and lipid‐lowering …

Mapping SLCO1B1 Genetic Variation for Global Precision Medicine in Understudied Regions in Africa: A Focus on Zulu and Cape Admixed Populations

N Hoosain, B Pearce, C Jacobs… - OMICS: A Journal of …, 2016 - liebertpub.com
Abstract The US President Barack Obama has announced, in his State of the Union address
on January 20, 2015, the Precision Medicine Initiative, a US $215-million program. For …

Prevalence of SLCO1B1 single nucleotide variations and their association with hypercholesterolaemia in hypercholesterolemic patients in Gauteng, South Africa

R De Beer, K Outhoff, A Phulukdaree, P Soma - Xenobiotica, 2021 - Taylor & Francis
Statins, the standard treatment for hypercholesterolaemia, among the most widely
prescribed, have been associated with side effects, including statin intolerance. The aim of …

[HTML][HTML] Pharmacogenetic analysis of inter-ethnic variability in the uptake transporter SLCO1B1 gene in Colombian, Mozambican, and Portuguese populations

MH Nega, DF Berhe, V Ribeiro - BMC Medical Genomics, 2023 - Springer
Background Statin-induced myopathy is reported to be associated with the solute carrier
organic anion transporter family member 1B1 gene single nucleotide polymorphism, c. 521 …

Polymorphism analysis of APOE and SLCO1B1 genes in Meizhou area of southern China

H Wu, H Wu, Z Yu, Q Zhu, Q Zhang, Q Huang, Z Zhong - 2019 - researchsquare.com
Background APOE and SLCO1B1 genetic polymorphisms are relevant in statin
pharmacokinetics. Objective Aim of this study was to investigate the polymorphisms of APOE …