Real-world effectiveness and safety of ustekinumab in elderly Crohn's disease patients

R Garg, M Aggarwal, R Butler, JP Achkar… - Digestive diseases and …, 2022 - Springer
Introduction The efficacy and safety profile of ustekinumab (UST) in Crohn's disease (CD) is
favorable; however, data in elderly patients are lacking. We aimed to assess the safety and …

Vedolizumab has longer persistence than infliximab as a first-line biological agent but not as a second-line biological agent in moderate-to-severe ulcerative colitis …

A Pudipeddi, Y Ko, S Paramsothy… - Therapeutic Advances …, 2022 - journals.sagepub.com
Background: The choice between infliximab (IFX) and vedolizumab (VED) as a first-line
biological agent in moderate-to-severe ulcerative colitis (UC) can be difficult. Second-line …

Safety, effectiveness, and treatment persistence of subcutaneous vedolizumab in IBD: a multicenter study from the United Kingdom

SH Lim, B Gros, E Sharma, A Lehmann… - Inflammatory Bowel …, 2024 - academic.oup.com
Abstract Background and Aims Despite intravenous (IV) vedolizumab being established for
treatment of inflammatory bowel disease (IBD), the novel subcutaneous (SC) route of …

Vedolizumab is superior to infliximab in biologic naïve patients with ulcerative colitis

R Sablich, MT Urbano, M Scarpa, F Scognamiglio… - Scientific Reports, 2023 - nature.com
There are no prospective, head-to-head, controlled trials comparing the efficacy and safety
of Infliximab (IFX) and Vedolizumab (VDZ) for the treatment of moderate-to-severe ulcerative …

Real-world effectiveness of vedolizumab in inflammatory bowel disease: week 52 results from the Swedish prospective multicentre SVEAH study

C Eriksson, S Rundquist… - Therapeutic …, 2021 - journals.sagepub.com
Background: Prospectively and systematically collected real-world data on vedolizumab are
scarce. We aimed to assess the long-term clinical effectiveness of vedolizumab in …

First-line biologics or small molecules in inflammatory bowel disease: a practical guide for the clinician

S Chang, D Hudesman - Current gastroenterology reports, 2020 - Springer
Abstract Purpose of Review Treating moderate-to-severe inflammatory bowel disease has
become increasingly complex as the array of available biologics increases. Moreover …

Real-world effectiveness and safety of vedolizumab for the treatment of inflammatory bowel disease: the Scottish vedolizumab cohort

N Plevris, CS Chuah, RM Allen, ID Arnott… - Journal of Crohn's …, 2019 - academic.oup.com
Abstract Background & Aims Vedolizumab is an anti-a4b7 monoclonal antibody that is
licensed for the treatment of moderate to severe Crohn's disease and ulcerative colitis. The …

[HTML][HTML] Novel oral-targeted therapies for mucosal healing in ulcerative colitis

E Antonelli, V Villanacci, G Bassotti - World journal of …, 2018 - ncbi.nlm.nih.gov
Ulcerative colitis (UC), a chronic, relapsing, remitting disease of the colon and rectum, is
characterized by inflammatory ulceration of the mucosa. Current UC therapy relies on …

Influence of drug exposure on vedolizumab-induced endoscopic remission in anti-tumour necrosis factor [TNF] naïve and anti-TNF exposed IBD patients

B Verstockt, E Mertens, E Dreesen… - Journal of Crohn's …, 2020 - academic.oup.com
Abstract Background and Objectives Vedolizumab has demonstrated efficacy and safety in
patients with Crohn's disease [CD] and ulcerative colitis [UC]. Endoscopic outcome data are …

[HTML][HTML] Approach to loss of response to advanced therapies in inflammatory bowel disease

N Vootukuru, A Vasudevan - World Journal of Gastroenterology, 2024 - ncbi.nlm.nih.gov
BACKGROUND Remarkable progress over the last decade has equipped clinicians with
many options in the treatment of inflammatory bowel disease. Clinicians now have the …