Sepsis‑induced cardiac dysfunction and pathogenetic mechanisms

J Song, X Fang, K Zhou, H Bao… - Molecular Medicine …, 2023 - spandidos-publications.com
Sepsis is a manifestation of the immune and inflammatory response to infection, which may
lead to multi‑organ failure. Health care advances have improved outcomes in critical illness …

[HTML][HTML] Roles of distinct nuclear receptors in diabetic cardiomyopathy

Y Zheng, Y Xu, L Ji, W San, D Shen, Q Zhou… - Frontiers in …, 2024 - frontiersin.org
Diabetes mellitus induces a pathophysiological disorder known as diabetic cardiomyopathy
and may eventually cause heart failure. Diabetic cardiomyopathy is manifested with systolic …

Mechanism of Shenfu injection in suppressing inflammation and preventing sepsis-induced apoptosis in murine cardiomyocytes based on network pharmacology and …

P Huang, Y Guo, X Hu, X Fang, X Xu, Q Liu - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Shenfu injection (SFI), as a famous classical Chinese
patent medicine injection for the treatment of sepsis, has achieved good curative effects in …

[HTML][HTML] Energy metabolism and redox balance: How phytochemicals influence heart failure treatment

C Chen, J Wang, X Zhu, J Hu, C Liu, L Liu - Biomedicine & …, 2024 - Elsevier
Heart Failure (HF) epitomizes a formidable global health quandary characterized by marked
morbidity and mortality. It has been established that severe derangements in energy …

[HTML][HTML] Energy Metabolism: From Physiological Changes to Targets in Sepsis-induced Cardiomyopathy

D Ni, X Lin, C Deng, L Yuan, J Li, Y Liu, P Liang… - Hellenic Journal of …, 2024 - Elsevier
Sepsis is a systemic inflammatory response syndrome caused by a variety of dysregulated
responses to host infection with life-threatening multi-organ dysfunction. Among the injuries …

[HTML][HTML] PPARA ameliorates sepsis-induced myocardial injury via promoting macrophage M2 polarization by interacting with DUSP1

L Cheng, D Liu, S Gao - Regenerative Therapy, 2024 - Elsevier
Background The morbidity and mortality of sepsis are increasing year by year. Statistically,
40–50% of patients with sepsis have concomitant myocardial injury, and its mortality rate is …

[PDF][PDF] 线粒体质量控制系统在脓毒性心肌病发病中的研究进展

解有成, 肖曙芳, 林雪梅, 陈顺, 徐进… - 中国比较医学 …, 2024 - zgbjyx.cnjournals.com
脓毒性心肌病(septic cardiomyopathy, SIC) 是脓毒症中常见的器官功能障碍,
其与患者高死亡率和不良预后密切相关. SIC 发病机制复杂且缺乏有效的治疗手段是亟待解决的 …