Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …

There are at least 21 families of enveloped viruses that infect mammals, and many contain
members of high concern for global human health. All enveloped viruses have a dedicated …

SARS-CoV-2 infection causes spike-dependent fusion of infected cells with ACE2 positive
neighboring cells, generating multi-nuclear syncytia that are often associated with severe …

Viral spillover from animal reservoirs can trigger public health crises and cripple the world
economy. Knowing which viruses are primed for zoonotic transmission can focus …

Natural extracts have been and continue to be used to treat a wide range of medical
conditions, from infectious diseases to cancer, based on their convenience and therapeutic …

Severe cardiovascular complications can occur in coronavirus disease of 2019 (COVID-19)
patients. Cardiac damage is attributed mostly to the aberrant host response to acute …

The intentional use of viruses for cancer therapy dates back over a century. As viruses are
inherently immunogenic and naturally optimized delivery vehicles, repurposing viruses for …

Abstract SARS-CoV-2, the causative agent of COVID-19, has caused an unprecedented
global health crisis. The SARS-CoV-2 spike, a surface-anchored trimeric class-I fusion …

We are currently in a rapidly expanding pandemic of the SARS-CoV-2 virus, which
originated in the city of Wuhan in central China. The COVID-19 is now spread worldwide …

A distinctive feature of the SARS-CoV-2 spike protein is its ability to efficiently fuse cells, thus
producing syncytia found in COVID-19 patients. This commentary proposes how this ability …